ID A0A1G6YHU3_9PROT Unreviewed; 1047 AA.
AC A0A1G6YHU3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Multidrug efflux pump subunit AcrB {ECO:0000313|EMBL:SDD90064.1};
GN ORFNames=SAMN04488071_1637 {ECO:0000313|EMBL:SDD90064.1};
OS Kordiimonas lacus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Kordiimonadales;
OC Kordiimonadaceae; Kordiimonas.
OX NCBI_TaxID=637679 {ECO:0000313|EMBL:SDD90064.1, ECO:0000313|Proteomes:UP000183685};
RN [1] {ECO:0000313|EMBL:SDD90064.1, ECO:0000313|Proteomes:UP000183685}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.9109 {ECO:0000313|EMBL:SDD90064.1,
RC ECO:0000313|Proteomes:UP000183685};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNAK01000003; SDD90064.1; -; Genomic_DNA.
DR RefSeq; WP_068302639.1; NZ_LRUA01000002.1.
DR AlphaFoldDB; A0A1G6YHU3; -.
DR STRING; 637679.GCA_001550055_01319; -.
DR OrthoDB; 174266at2; -.
DR Proteomes; UP000183685; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF33; RND SUPERFAMILY EFFLUX PUMP PERMEASE COMPONENT; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000183685};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 862..880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 887..907
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 913..938
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 990..1023
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT COILED 572..599
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1047 AA; 116598 MW; 138868640C01165E CRC64;
MNGLIEWWAR NKVAANLLMF GIFMSGFFAF TSMERELDPQ VRFPGLQIVV AWPGASPVEV
EEQIVARIEE SVRDLDNIEW VRSFAGESSG EVYILAEQSV DFTQFMNDVK IRVDSISSFP
RDIEPPRVQQ WVNRNEMIRV AVHGDIGERP LKRLAEKLRR EAAQLPAVNI VELFGVRREE
VSIEVSENSL RRYNISFADV AAVIRANSLN SSGGTVRTDA GEYKLTARNM ADTKADFENI
IVRQTADGGT IRVGDVATVI DGFEDNEILA TLNGEPAVLL QVMTTEVMDI VTASESINKW
VDERSKTLPT GAKLTLWTDN SELFKGRMET IGSSAFWGLV LVVIVLMLTL RPKVAFWVAF
GIATAYAGAF VFLPSLGISI NFLSTFAFLL VLGIVVDDAI VVGESIHTES QKTGGGITAA
VFGTQLVAKP VIFAVLTTII AFLPWVFIDG STSEFTRHIT WVVICALAFS LVESLLILPA
HLSGLKPRQN LSRFGKFQKR IADGITTFAH NHYRGIGQWA VKRRYLTFSV FVAVFIVALG
LFNVGYVKKA FMPDIESDEI NVNVVLPEGA SYNRALEILA QLQAAEEELV REVDASTNTE
GALIENWYTR SRRDSVIAIV KLTPPEERPE AVQSMTAKET ALRLRDLIGV IPDAKEVTVH
YSSNDNDPGF ELSVRHSDLD LLREAVNDLE DQLRTYDALY DVRNNLEGAS EEIRIELMPG
AEKLGLTLAD VTRQVRQAYY GEEVQRLPRD GQDVKVMVRY PRESRRSIES LKDFRVRTAD
GEEVPLMSIA ELRYAPGINR IARWNMNRAA RVSADMKENI REDIMKDLNE NFFPEWEKQY
PGIIRGAIGQ AEGEARFIAQ VLKLYATALF VMYAMLAIAF RSYWQPIAIL IAMPYALAGA
IFGHLAVDMT MAIFSYFGIA AAMGVVVNDN LVLVDYCNKL RERGMDPYEA IVEAGVARFR
PILLTSVTTF VGLVPMMLER SIQAAFLKPI VVALAGGVLI AFFVTLFMVP ALYTIGFDIG
GFFGRMWAGA KRRFKGQPKG SLPQQAE
//
