ID A0A1G6ZZL4_9FLAO Unreviewed; 466 AA.
AC A0A1G6ZZL4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Exodeoxyribonuclease 7 large subunit {ECO:0000256|RuleBase:RU004355};
DE EC=3.1.11.6 {ECO:0000256|RuleBase:RU004355};
GN ORFNames=SAMN05421636_103137 {ECO:0000313|EMBL:SDE07086.1};
OS Pricia antarctica.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Pricia.
OX NCBI_TaxID=641691 {ECO:0000313|EMBL:SDE07086.1, ECO:0000313|Proteomes:UP000199109};
RN [1] {ECO:0000313|EMBL:SDE07086.1, ECO:0000313|Proteomes:UP000199109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23421 {ECO:0000313|EMBL:SDE07086.1,
RC ECO:0000313|Proteomes:UP000199109};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-
CC direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
CC Evidence={ECO:0000256|RuleBase:RU004355};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU004355}.
CC -!- SIMILARITY: Belongs to the XseA family.
CC {ECO:0000256|RuleBase:RU004355}.
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DR EMBL; FNAO01000003; SDE07086.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6ZZL4; -.
DR STRING; 641691.SAMN05421636_103137; -.
DR OrthoDB; 9802795at2; -.
DR Proteomes; UP000199109; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR CDD; cd04489; ExoVII_LU_OBF; 1.
DR InterPro; IPR003753; Exonuc_VII_L.
DR InterPro; IPR020579; Exonuc_VII_lsu_C.
DR InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR NCBIfam; TIGR00237; xseA; 1.
DR PANTHER; PTHR30008; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR PANTHER; PTHR30008:SF0; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR Pfam; PF02601; Exonuc_VII_L; 1.
DR Pfam; PF13742; tRNA_anti_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000256|RuleBase:RU004355};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004355};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|RuleBase:RU004355};
KW Reference proteome {ECO:0000313|Proteomes:UP000199109}.
FT DOMAIN 12..118
FT /note="OB-fold nucleic acid binding"
FT /evidence="ECO:0000259|Pfam:PF13742"
FT DOMAIN 142..458
FT /note="Exonuclease VII large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02601"
SQ SEQUENCE 466 AA; 52491 MW; 671BC10142518EAB CRC64;
MSEKVNGKHI FSLLEVTKSI QKTITNRYQT AFWVKAEMNK LNHYQRSGHC YPELVEKKEG
KVIAQISAIL WKSDYQKINT NFQRVLKEPL KDGIKILFSA TINFDPKYGL TLQINDIDPS
FTLGDLEKEK QDTINKLRLA GIFSKNKQLA LPVLPQRIAI ISVETSKGYA DFLNVFESAG
RSWNYTFFQL LFPSLLQGDN AVRTIIAQLR RIKKVIHHFD VVAIVRGGGG DIGLSCYNNY
DLAKEIAEFP IPVITGIGHS TNETVAELIA HENAITPTKL AEFLIQKFHD FSVPVHKAEE
KIIDRSRSLI RDAQTKFASE VKLLRSVTRN ILDKNKNAVR QQAQSLSQQS RFRLGNEKKV
LTAAGEDIRK GTYQFCTAQK HHTSYLTADL KKAIHRQLAQ KSLGLKNLET NIHNLSPQNV
LKRGYSITQL AGKAIRSTEQ VNPGDLLTTV LYEGSVSSTV QSTKKA
//
