ID   A0A1G7A842_9ACTN        Unreviewed;       538 AA.
AC   A0A1G7A842;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Bifunctional non-homologous end joining protein LigD {ECO:0000313|EMBL:SDE10657.1};
GN   ORFNames=SAMN04489747_2530 {ECO:0000313|EMBL:SDE10657.1};
OS   Auraticoccus monumenti.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Propionibacteriaceae; Auraticoccus.
OX   NCBI_TaxID=675864 {ECO:0000313|EMBL:SDE10657.1, ECO:0000313|Proteomes:UP000198546};
RN   [1] {ECO:0000313|EMBL:SDE10657.1, ECO:0000313|Proteomes:UP000198546}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MON 2.2 {ECO:0000313|EMBL:SDE10657.1,
RC   ECO:0000313|Proteomes:UP000198546};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629688; SDE10657.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G7A842; -.
DR   STRING; 675864.SAMN04489747_2530; -.
DR   OrthoDB; 9802472at2; -.
DR   Proteomes; UP000198546; Chromosome i.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR   InterPro; IPR014144; LigD_PE_domain.
DR   InterPro; IPR014145; LigD_pol_dom.
DR   NCBIfam; TIGR02777; LigD_PE_dom; 1.
DR   PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR   PANTHER; PTHR42705:SF2; MULTIFUNCTIONAL NON-HOMOLOGOUS END JOINING DNA REPAIR PROTEIN LIGD; 1.
DR   Pfam; PF13298; LigD_N; 1.
DR   Pfam; PF21686; LigD_Prim-Pol; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198546}.
FT   DOMAIN          43..150
FT                   /note="DNA ligase D 3'-phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF13298"
FT   DOMAIN          269..524
FT                   /note="DNA ligase D polymerase"
FT                   /evidence="ECO:0000259|Pfam:PF21686"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   538 AA;  59964 MW;  085C78180FC71648 CRC64;
     MAGRGEDERP LQRYQSMRHF DRTPEPAGRP GTAPEGTPRF VVQRHRARAL HYDVRFEIGG
     VLVSWAVPKG PTLDPDVRRL AVHVEDHPLE YIDFEGVIPS GEYGGGDVIV WDAGTWEPAE
     GVDPVEELAT GTLHARMHGE KLRGQFVLVR TRRQGSSSGG KEQWMMLHKH DEDAVTGWDA
     ADHPLSVLSG RTNEEVQADP DRLWRSDLPA DEASVELKVP VPDPPGEEEL AALDALEKQG
     RWEVLGRTLK VTNLDKELFP GRDGQPPVTK RDLVRYAAQV APTLLPYLAG RALNMNRFPG
     GAQTKGFWHK ELPTHAPEWV PRWENPAADP GETRTYLVVD EAAALVWAAN FGALEWHPWT
     SPTAAPDRPS YVLFDIDPGE QTTWEEVLVM ARLHRTALEH LGVRGRPKVT GRRGVQIWVP
     IRPGPTFDQT RAWAETVSRS VGAVVPELVS WKWTVRDRGG LARLDYTQNA VNKTLVAPYS
     PRPSAGAPVS VPIEWDELDD PALRPDGFLL RDVVPRLLER GDLFADVLDH DQDLPTVT
//