ID   A0A1G7ADX2_9ACTN        Unreviewed;       333 AA.
AC   A0A1G7ADX2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase {ECO:0000313|EMBL:SDE12883.1};
GN   ORFNames=SAMN05216270_11381 {ECO:0000313|EMBL:SDE12883.1};
OS   Glycomyces harbinensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Glycomycetales; Glycomycetaceae;
OC   Glycomyces.
OX   NCBI_TaxID=58114 {ECO:0000313|EMBL:SDE12883.1, ECO:0000313|Proteomes:UP000198949};
RN   [1] {ECO:0000313|EMBL:SDE12883.1, ECO:0000313|Proteomes:UP000198949}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.3516 {ECO:0000313|EMBL:SDE12883.1,
RC   ECO:0000313|Proteomes:UP000198949};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; FNAD01000013; SDE12883.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G7ADX2; -.
DR   STRING; 58114.SAMN05216270_11381; -.
DR   OrthoDB; 9797931at2; -.
DR   Proteomes; UP000198949; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08234; threonine_DH_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43401:SF5; ALCOHOL DEHYDROGENASE-RELATED; 1.
DR   PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          24..130
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          173..293
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   333 AA;  34875 MW;  99FBE9ADC8FF7B7F CRC64;
     MRAVVIEAPG RINVTTVDDP KPGPREVVVE VAGAGICGTD LHIIDGDLEG TVYPIVPGHE
     FAGTVAAVGK AVTEFAVGDR VAVDPNVFCG ECHYCKIGHG NLCERYNAIG VISSPGAAAQ
     YCAAPVANCY LLPESVPLEH APLIEPLSCA VHGFDLLPGR VGEHYLVYGA GTMGLMMAQL
     ARFSGAASVS VVDLNTDRLP VAAGLGADRV AASAAELDRP EGWEVVIDCT GAVPAIEDGL
     TRVRKGGTFQ VFGVAPEAAT ASFSPFRVYK DEIHIVGSMA VLHSFGRAVD LLAKRVVDPD
     VMISHRFGLD DYESAVDAFR KGTGRKLQVQ PAA
//