ID   A0A1G7APJ4_9BURK        Unreviewed;       309 AA.
AC   A0A1G7APJ4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=Glyoxylate/hydroxypyruvate reductase A {ECO:0000313|EMBL:SDE16731.1};
GN   ORFNames=SAMN05444679_11859 {ECO:0000313|EMBL:SDE16731.1};
OS   Variovorax sp. CF079.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=1882774 {ECO:0000313|EMBL:SDE16731.1, ECO:0000313|Proteomes:UP000198763};
RN   [1] {ECO:0000313|EMBL:SDE16731.1, ECO:0000313|Proteomes:UP000198763}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF079 {ECO:0000313|EMBL:SDE16731.1,
RC   ECO:0000313|Proteomes:UP000198763};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMZU01000018; SDE16731.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G7APJ4; -.
DR   STRING; 1882774.SAMN05444679_11859; -.
DR   OrthoDB; 9787219at2; -.
DR   Proteomes; UP000198763; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   CDD; cd12164; GDH_like_2; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Pyruvate {ECO:0000313|EMBL:SDE16731.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198763}.
FT   DOMAIN          100..272
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
SQ   SEQUENCE   309 AA;  33904 MW;  C3137EB1A7F05D4B CRC64;
     MRITVCLTDN RPDAWIEGLR AALPEAVVEN WRPGTPQADH AVVWAPPQAF IDEQPKLRGI
     FNIGAGVDAL LKLKLPPEAQ VVRLDDAGMS VQMAEYVCHA LIRHFREFDI YEADAREGRW
     SFRKPRERED FAVGVMGLGV LGERVAKAVA QFEFPVNGWS RSPKAIEGLR CFAGEAEFNA
     FLGASRVLVN LLPLTEATRG ILNRENLSRL NGGGPGGYLI NVARGAHLVE SDLIPLLDSG
     QLAGATLDVF EVEPLPTEHP FWRHPKITVT PHGSARTVRE ASIAQIADKI RAVEKGEPIA
     GVVGRERGY
//