ID A0A1G7CS29_9PROT Unreviewed; 393 AA.
AC A0A1G7CS29;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Acetyl-CoA C-acetyltransferase {ECO:0000313|EMBL:SDE42109.1};
GN ORFNames=SAMN04488071_2919 {ECO:0000313|EMBL:SDE42109.1};
OS Kordiimonas lacus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Kordiimonadales;
OC Kordiimonadaceae; Kordiimonas.
OX NCBI_TaxID=637679 {ECO:0000313|EMBL:SDE42109.1, ECO:0000313|Proteomes:UP000183685};
RN [1] {ECO:0000313|EMBL:SDE42109.1, ECO:0000313|Proteomes:UP000183685}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.9109 {ECO:0000313|EMBL:SDE42109.1,
RC ECO:0000313|Proteomes:UP000183685};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; FNAK01000006; SDE42109.1; -; Genomic_DNA.
DR RefSeq; WP_068306561.1; NZ_LRUA01000006.1.
DR AlphaFoldDB; A0A1G7CS29; -.
DR STRING; 637679.GCA_001550055_03002; -.
DR OrthoDB; 7181944at2; -.
DR Proteomes; UP000183685; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF144; ACYL-COA THIOLASE-RELATED; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000183685};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:SDE42109.1}.
FT DOMAIN 6..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 270..391
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 90
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 349
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 379
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 393 AA; 40270 MW; B4487A7A78565BF8 CRC64;
MSQDAIVIVG MARTPMGGLL GDLSTVPASD LGAVAIQGAL ASAGIEGEAV NETIMGCVLP
AGQGQAPARQ ASRKAGIPDV TGAVTINKMC GSGMQAMMQA HDSLKAGTNS VVVAGGMESM
SLAPHILPTG RTGVKYGNAQ MLDHMALDGL TDAYAGEPMG VFAELCAAEY QFTREAQDAY
AIRSLERAQR AIEDGSFDGE VVPVTVKSRR GDLEVATDEQ PPKARLDKIP GLRPAFKKDG
TVTAANASSI SDGAAALVMM TAGEAEKRGL KPLAKLVAHA NHGQAPEWFT TAPVKAMEKV
LDKAGWTVAD VDLFEVNEAF AVVAMAAIQE LGLDPEKVNV NGGACALGHP IGASGARICV
TLINALKKRG LKKGVASLCI GGGEATAVAI ELA
//
