ID A0A1G7IMB0_9BACT Unreviewed; 1010 AA.
AC A0A1G7IMB0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN05444167_1491 {ECO:0000313|EMBL:SDF13439.1};
OS Terriglobus roseus.
OC Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC Terriglobus.
OX NCBI_TaxID=392734 {ECO:0000313|EMBL:SDF13439.1, ECO:0000313|Proteomes:UP000182427};
RN [1] {ECO:0000313|EMBL:SDF13439.1, ECO:0000313|Proteomes:UP000182427}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAS232 {ECO:0000313|EMBL:SDF13439.1,
RC ECO:0000313|Proteomes:UP000182427};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; LT629690; SDF13439.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G7IMB0; -.
DR Proteomes; UP000182427; Chromosome i.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000182427};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 388..640
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 659..1002
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1010 AA; 111270 MW; FA024F4EBF7380C5 CRC64;
MAPEKKTGPS TPLHSDQEGS VAVEQKAVSP NDHIVIRGAR THNLKGIDVN IPHNMLTVVS
GVSGSGKSSL AFDTVYAEGQ RRYVESLSAY ARQFLERIEK PDVEHMDGLA PAIAIKQKNQ
TRNPRSTVAT ATEIYDYMRL LYARCGTVTC IHCGGIVKRD TVDEIAAAVL AMEEGARLYA
LFPIIRREVV LEPMQEFALP VEEEAPKPKP KKVATKKTKA AEQTIVDPSE PLKERLVELR
RRGFNRLFQN GNIVEFSTPE SLLELNFSEP IYVLADRLSV SADVRSRIVD AIETGYRESG
EIVFLTAPRD ESEPKRLRFS AAFECVNCHR AYRDPEPRLF SFNNPYGACP RCQGFGNTID
FDPDLIIPDK SKTLDEGAID PWTKPKYREY HGVMKRFAQA NNIPLKTPWY DLTPAQQNAI
WDGGTGFPGI RGFFRLLDTK KYKLHVRVFL SKYRGYAPCP DCRGQRLRAE ARAVLLNEKN
ICEAAGLTIS AARAFFDGLK LSPAQTEIAG KILEEVRQRI SFLEQVGLEY LTLDRLSSTL
SGGESQRIQL ATSLGSRLVG ALYVLDEPSI GLHSRDTAKL VKILHELRDL GNTILVVEHD
PDVITSADRL IDLGPGAGEL GGQLLATGTV AEIRKDDHSI TGKYLSGRSR IPVPAERREP
TREMLKLKGA RIHNLRGVDI EIPLGMLTVV TGVSGSGKST IVHQVLHRAL EFSLGVEGVS
SDVQQLYREI TGTHFIREVV LVDQSPIGRT PRSNPVTYIK AFDAIRELFA SQPDARRKGY
TAGSFSFNVP GGRCDTCEGD GTVTVEMQFL ADVELPCEEC NGTRYKPGIL DIKYKNRNIH
DVLNMTVRDA VHYFAGNPKI VDRLQVLEEV GLGYVRLGQS ATTLSGGEAQ RVKLASHLAN
IRSTSPRGET KKAASRVLYI LDEPTTGLHF ADVATLLQAF RKLIDGGGSL LVIEHNMDII
KSADWIIDMG PEGGSAGGQV VAVGTPEEIA RVPESYTGRF LKPVLEGAVA
//
