ID   A0A1G7LI69_9ACTN        Unreviewed;      1008 AA.
AC   A0A1G7LI69;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Ribonuclease E {ECO:0000313|EMBL:SDF49175.1};
GN   ORFNames=SAMN05660662_2333 {ECO:0000313|EMBL:SDF49175.1};
OS   Blastococcus aurantiacus.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Blastococcus.
OX   NCBI_TaxID=1550231 {ECO:0000313|EMBL:SDF49175.1, ECO:0000313|Proteomes:UP000199406};
RN   [1] {ECO:0000313|EMBL:SDF49175.1, ECO:0000313|Proteomes:UP000199406}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44268 {ECO:0000313|EMBL:SDF49175.1,
RC   ECO:0000313|Proteomes:UP000199406};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR   EMBL; FNBT01000004; SDF49175.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G7LI69; -.
DR   STRING; 1550231.SAMN05660662_2333; -.
DR   Proteomes; UP000199406; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd04453; S1_RNase_E; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR   InterPro; IPR004659; RNase_E/G.
DR   InterPro; IPR003029; S1_domain.
DR   NCBIfam; TIGR00757; RNaseEG; 1.
DR   PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR   PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR   Pfam; PF10150; RNase_E_G; 1.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50126; S1; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          396..473
FT                   /note="S1 motif"
FT                   /evidence="ECO:0000259|PROSITE:PS50126"
FT   REGION          1..112
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..342
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          768..919
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          974..1008
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..49
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        135..149
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..183
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        184..203
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..266
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..342
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        780..804
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        851..871
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1008 AA;  106955 MW;  D0F2190912685D3B CRC64;
     MADTDNSTPT ADETPTGPRP DDTVTEVPAV SEDSSVPEDP DEEADDATAG EPPAEPQPEP
     EAPTDAEPEP VGSRFGAQFS SPEPTAVVAR PRRRATRPAA APDPDAVEPV TPAAPAAAVP
     AFVSFMAPPV DAPPAPRRRS RRPAESPEIE PDEAEAPEVP AEEAEPARGR QRSRRRPAAA
     PVEDVEPIED EDTDDETGAV DDDGDSGDGT GSRRRRRGRR GRGRGRTGED AGDAEDENGE
     QSPVADTETD DDSADGDDDE TDGDSDEASG GSSTRRRRRR RRRSGSAGED ASDDTDDDDR
     PERAGRNGRT TSDDDVRGVA GSTRLEAKRQ RRRDGRDTGR RRAPILTESE FLARREAVDR
     KMVIRQRGER TQIAVLEDDV LVEHYVTQAQ ATSFAGNVYL GRVQNVLPSM EAAFIDIGKG
     RNAVLYAGEV NWDAAGLSGK QRSIETAMKS GDKVLVQVTK DPIGHKGARL TQQINLPGRF
     LVYVPGGSMT GISRKLPDTE RQRLKDILKR IVPEDAGVII RTAAEGASEE ELTRDVNRLK
     AQWEVISQKA ESTSNAPTLL YGEPDLAIRV IRDVFNEDFK DLVVQGDDAW DTVEAYVGHV
     SPELSSRLSR YTGQGDVFHD LRIDEQLAKA LDRKVWLPSG GSLVIDRTEA MTVVDVNTGK
     FVGSGGNLEQ TVTRNNMEAA EEIVRQLRLR DIGGIIVIDF IDMVLESNRD LVLRRLTECL
     GRDRTKHQVA EVTSLGLVQM TRKRVGQGLL EVFSETCEHC RGRGVLISTD PVDEKRRSGN
     GSGGGNSGGG NSGGGNSGGG NSGGGNSGGG RRDRSGKGDG GGRDDSATEQ PATIESAPAE
     PAAEADGETP EGTRSGGRRN RGRRNRGQSG EERAAADAAV LAGTGGDDAE AADVVPVEDV
     APVNADAEAG PATPPRESTD VVVVPPLAVA EPAVEQAPEP AAEDVATDEV PIEEPEIEAG
     PEIAAVEVAA VEAAAAESAP TEPAAPAAPA GRPRRRRAAS RPAGPPVV
//