ID   A0A1G7MLR1_9BACL        Unreviewed;       914 AA.
AC   A0A1G7MLR1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:SDF62682.1};
GN   ORFNames=SAMN04488542_11413 {ECO:0000313|EMBL:SDF62682.1};
OS   Fontibacillus panacisegetis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Fontibacillus.
OX   NCBI_TaxID=670482 {ECO:0000313|EMBL:SDF62682.1, ECO:0000313|Proteomes:UP000198972};
RN   [1] {ECO:0000313|EMBL:SDF62682.1, ECO:0000313|Proteomes:UP000198972}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 28129 {ECO:0000313|EMBL:SDF62682.1,
RC   ECO:0000313|Proteomes:UP000198972};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; FNBG01000014; SDF62682.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G7MLR1; -.
DR   STRING; 670482.SAMN04488542_11413; -.
DR   OrthoDB; 9764050at2; -.
DR   Proteomes; UP000198972; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10814; GH38N_AMII_SpGH38_like; 1.
DR   Gene3D; 2.60.40.2210; -; 1.
DR   Gene3D; 2.60.40.2220; -; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041509; GH38_beta-1.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF18438; Glyco_hydro_38; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198972}.
FT   DOMAIN          297..370
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   914 AA;  103086 MW;  A5A8D76ADED059E9 CRC64;
     MNKQKRAHII SHTHWDREWY LPYEKHHVRL VALVDSLLDK LDKGSDFRSF YLDGQTIILE
     DYLQVRPENK ERLEKHIREG RILIGPWYIL QDAFLTSGEA NVRNMQIGHR DAKQYGEPAK
     IGYFPDTFGL VGQTPQLMQQ SGISNAFFGR GVKPTGFNNT VSDGGYESSF SELIWEGPDG
     SKVLGILFAN WYSNGNEVPV DEAEAKTFWD KKLADAEKYA ATGELLFMNG CDHQPIQLDL
     PEAIETASRL YSDTEFIHSS LPEYLQSLEG ALDRDLSSVK GELRSQRTDG WGTLVNTASA
     RVYLKQMNQE GQALLEKVAE PLASFAHLLG QSYPHHLFTY AWKTLMQNHP HDSICGCSVD
     EVHREMVTRF DKSRHVAEAI IDESKQVIAE KVDTSVFCEY GEDPLPLIAM NTTGWARSGV
     LSVELDAARL YLREGFTLEE TSRRMKETDL SGRVLVDEQG NAVPCSVEDL GLLFGYDLPE
     DKFRQPYMCR RVRITFQAKE VPALGLRAYA WVRREEQQQE AASLLTGQRV MENEALKVEI
     AEDGSFALIH KKTGQTYRDL GVYEDTGDIG NEYMYRQPEG EEALTTKGLA AQIRVLEDTP
     YRASVEIVHE LEIPVSGDEK LDQEQRELVY YPERKAQRSD SLVPLRICTV ITLEADAKGV
     FVETKLNNQA KDHRLRALFP TDLDAATHLA DSMFEIAERD NVPASEWENP SNTQHQQAFV
     DIKDAHSGLT IANLGLNEYE VLRDGRNTIA ITLLRAVGEL GDWGLFPTPE AQCLGEHTFR
     MELIPYCADD EANGAFEAYT EAYQFQIPWT VCQTGVHSGQ IAPIYTPLRW ESAELAFSSM
     KMNEDTDNLL LRWFNMSGSN TQLIFSTKIS VESMYKTTIM EELAPPIART AVGELNVAVG
     PCEIVTIGMK PILP
//