ID A0A1G7QAF3_9BACT Unreviewed; 751 AA.
AC A0A1G7QAF3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Transporter, CPA2 family {ECO:0000313|EMBL:SDF95531.1};
GN ORFNames=SAMN05216518_11638 {ECO:0000313|EMBL:SDF95531.1};
OS Bacteroidales bacterium KHT7.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales.
OX NCBI_TaxID=1855373 {ECO:0000313|EMBL:SDF95531.1, ECO:0000313|Proteomes:UP000198526};
RN [1] {ECO:0000313|EMBL:SDF95531.1, ECO:0000313|Proteomes:UP000198526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KHT7 {ECO:0000313|EMBL:SDF95531.1,
RC ECO:0000313|Proteomes:UP000198526};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNBQ01000016; SDF95531.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G7QAF3; -.
DR STRING; 1855373.SAMN05216518_11638; -.
DR OrthoDB; 9781411at2; -.
DR Proteomes; UP000198526; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR42751:SF3; NA(+)_H(+) ANTIPORTER; 1.
DR PANTHER; PTHR42751; SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198526};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 527..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 580..664
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 669..751
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 751 AA; 82603 MW; 42601C2322A46EDB CRC64;
MGELPSLISD LALILVVAGC VSLLFKWLRQ PVVLGYIVAG FLASSHMPYT PSVIDTGNIH
LWADIGVIFL LFALGLEFSF KKIVKMGSAP VIAACSIIVC MIIVGVGVGK LFGWSQMDSL
FLGGMLAMSS TTIIYKAFDD LGLRQQKFAG LVLSVLIIED ILAIVLMVML STMAVSRSFE
GEKMIFSLLK LGGLLILWFI TGIFLLPLFF KKFKSMLSNE TMLIVALGLC FAMVVVADLC
GFSAAFGAFI MGSILAETLE AERIESLVSP VKDLFGAIFF VSVGMMVDPM MLIEYWKPIV
AITAAILIGQ SVLGTGSYLL SGQTLKVAIR SGFSMAQIGE FAFIIASLGV SLGVTSHFLY
PVVVAVSVIT TFITPYMIKA SNPAYDVAVR YMPSKIANLI DNYTSGGTLL IRHKNNWNRL
LKSILRVTVV YMVLSVATIL LAFHVLLPFL SELMPFRYAR WTVAVLTLLC IAPFIRAMIA
KKNRSEEFKA LWNDSRLNIA PLVMLVAARV LIALAMVVYV IGHLFGYSMS FSIAVGLVLI
FAMYSSKKLQ ERSIQLEKTF FNNLHSRERY AEAMGQKKGS YLTQLMSDEL HLASVSLPEN
SCWEGMTLKE LDLGNKFNIS VASVIRGSIR INIPVALTRL YPHDKLEVIG TDEQLTKFIE
AMNADVFENE EFDIDDREMK LVEFVITAES VFAGKSISQS GIKAKYHCLI VGIEVDGQIQ
MPNRDTVLSE GSVVWAVGEN ADVERLPDLR A
//
