ID   A0A1G7SHW7_9ACTN        Unreviewed;       332 AA.
AC   A0A1G7SHW7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Nucleoside-diphosphate-sugar epimerase {ECO:0000313|EMBL:SDG22593.1};
GN   ORFNames=SAMN05421505_102314 {ECO:0000313|EMBL:SDG22593.1};
OS   Sinosporangium album.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Sinosporangium.
OX   NCBI_TaxID=504805 {ECO:0000313|EMBL:SDG22593.1, ECO:0000313|Proteomes:UP000198923};
RN   [1] {ECO:0000313|EMBL:SDG22593.1, ECO:0000313|Proteomes:UP000198923}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CPCC 201354 {ECO:0000313|EMBL:SDG22593.1,
RC   ECO:0000313|Proteomes:UP000198923};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC       {ECO:0000256|ARBA:ARBA00009219}.
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DR   EMBL; FNCN01000002; SDG22593.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G7SHW7; -.
DR   STRING; 504805.SAMN05421505_102314; -.
DR   OrthoDB; 3174087at2; -.
DR   Proteomes; UP000198923; Unassembled WGS sequence.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198923}.
FT   DOMAIN          4..252
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   332 AA;  35574 MW;  FB21AF8BAEE568C7 CRC64;
     MKVLVTGGGG FLGQAVTRLL AEAGHQVSTV NRRHYAVLDT WDVDQRVGDI RNRDHVTAAV
     RGHDAVVHCA GRAGAYGPAA EYHDVNVLGT LNVLAACRAA GITRLVHTSS PAVVHDGGHL
     EGADETAPYA TRWTAAYPKT KAQAERLVLA ADGDDLATVA LRPHIIWGPG DPHFIPALLA
     MAKGGRLNML GAGTWLIDNV YIDNAAHAHL LALERLEPGS AIAGRAYFIT QGEPRPIGET
     IKHLLGAAGV RPTVRHIPVS LARLLAPAVE AAYRLRGPHA APPFNRFLVE QFTTAHWFTI
     AAARRDLGYS PLISFDEGLE ALREHLHKHP PA
//