ID   A0A1G7TKR7_9ACTN        Unreviewed;       748 AA.
AC   A0A1G7TKR7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=DNA helicase IV {ECO:0000313|EMBL:SDG35926.1};
GN   ORFNames=SAMN05660324_2520 {ECO:0000313|EMBL:SDG35926.1};
OS   Klenkia brasiliensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Klenkia.
OX   NCBI_TaxID=333142 {ECO:0000313|EMBL:SDG35926.1, ECO:0000313|Proteomes:UP000198863};
RN   [1] {ECO:0000313|EMBL:SDG35926.1, ECO:0000313|Proteomes:UP000198863}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44526 {ECO:0000313|EMBL:SDG35926.1,
RC   ECO:0000313|Proteomes:UP000198863};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNCF01000003; SDG35926.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G7TKR7; -.
DR   Proteomes; UP000198863; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          185..532
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   REGION          690..719
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        699..713
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         206..213
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   748 AA;  80640 MW;  10AACB6A74B8CD60 CRC64;
     MPDGEAISAA SLPRHPEHEV EQAYVSTAYE MLDKGLAAVE VTYNTYEEGN RATSFALKRA
     LDLLRNSRGS GQLVFGRVDR PHEEPLYIGR RRVHDETKNL LVAGWHSPAA QVFYEASPAQ
     PSGLALKRVF VEQDRVLSQV VDEITASTAV DVLAGRSDGP TPLSDALLIE LDRSRDGVMR
     EVVATIQAEQ FRAIRAPRQG VLVVQGGPGT GKTVVGLHRA AWQAFNDADL RRTGILVVAP
     STAFLSYMSG VLPSLDASDV LQVDLGSLYA GEALATGWER PETARIKGSA AMSEVLHRAL
     TARRGWAEGD LEFALGGARA SLTGDEVREL VTDAASRRLP HNQARDVLRQ SLSAAAFRAY
     SEAQAAAGRA VIATEPALRR LSTFTNALDR MWPTLTPEEM LRGVYGTQTW LVDAASGVLS
     ADERALLFRE PRSSIDDEPW TAADLFCLDE LSYLLNGEGR SYGHVVVDEA QDLSPMQARA
     LARRCPSGSF TLLGDLAQAT GQWIRDDWQE LTVHLHHQPA QIEDLTVGYR VPGPVVELAA
     GLLPHIAPDL AVPRSVRQGL GAPTVHVAAQ SDADLLATVV TLASADVEAG LTTAVVVPDQ
     DHAEVYEALT AKFADRVGDG AAEDFGRALT VVPVSMVKGL EFDAVYVVEP SAIAAGGADG
     LRRLYVAMTR CTQLLRLICT ADLPPGLRHL LPNEVPADQG RVDETDDVDD PRKPTAGPGL
     AELIDMLDDD DRELVVALVH RLARSTQR
//