ID   A0A1G7V186_9ACTN        Unreviewed;      1028 AA.
AC   A0A1G7V186;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Glutamate-ammonia-ligase adenylyltransferase {ECO:0000313|EMBL:SDG53517.1};
GN   ORFNames=SAMN05660324_2868 {ECO:0000313|EMBL:SDG53517.1};
OS   Klenkia brasiliensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Klenkia.
OX   NCBI_TaxID=333142 {ECO:0000313|EMBL:SDG53517.1, ECO:0000313|Proteomes:UP000198863};
RN   [1] {ECO:0000313|EMBL:SDG53517.1, ECO:0000313|Proteomes:UP000198863}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44526 {ECO:0000313|EMBL:SDG53517.1,
RC   ECO:0000313|Proteomes:UP000198863};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNCF01000004; SDG53517.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G7V186; -.
DR   OrthoDB; 9759366at2; -.
DR   Proteomes; UP000198863; Unassembled WGS sequence.
DR   GO; GO:0008882; F:[glutamate-ammonia-ligase] adenylyltransferase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   CDD; cd05401; NT_GlnE_GlnD_like; 2.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR   Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR   InterPro; IPR023057; GlnE.
DR   InterPro; IPR005190; GlnE_rpt_dom.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR   PANTHER; PTHR30621:SF0; BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME; 1.
DR   PANTHER; PTHR30621; GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE; 1.
DR   Pfam; PF08335; GlnD_UR_UTase; 2.
DR   Pfam; PF03710; GlnE; 2.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 2.
DR   SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000313|EMBL:SDG53517.1};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW   ECO:0000313|EMBL:SDG53517.1}; Transferase {ECO:0000313|EMBL:SDG53517.1}.
FT   DOMAIN          103..341
FT                   /note="Glutamate-ammonia ligase adenylyltransferase
FT                   repeated"
FT                   /evidence="ECO:0000259|Pfam:PF03710"
FT   DOMAIN          370..512
FT                   /note="PII-uridylyltransferase/Glutamine-synthetase
FT                   adenylyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF08335"
FT   DOMAIN          617..855
FT                   /note="Glutamate-ammonia ligase adenylyltransferase
FT                   repeated"
FT                   /evidence="ECO:0000259|Pfam:PF03710"
FT   DOMAIN          882..1021
FT                   /note="PII-uridylyltransferase/Glutamine-synthetase
FT                   adenylyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF08335"
SQ   SEQUENCE   1028 AA;  110335 MW;  761B628573F6CCC9 CRC64;
     MTDPVEVPRR AVVRLVRLGF EDGERVARLL ASPELGLWDL DRNEPADPEA APVVSALARA
     GDPDLAVLTL ARLVEALDRE DPGGELAAHL LSRLRGSANL RGQLLAVLGA SAGLDDHLVA
     HPEDWTVLDT DDGPVRPTPL SLEQQMLRAV GADPDDPPWG VGLGTPAPDA DVSRVRDLRR
     AYLRAVLSVA GRDLGGGLGA DEVAGELADL AGAVLVAGLA LAVADQPPGA PHCRIAVIGL
     GKCGGRELNY VSDVDVVFVA EPLDGADDAE ATATAAKVCA TLMRVCREAA WEVDAALRPE
     GKAGQLVRTL AGHVAYYEQW AGTWEFQALL KMRGVAGDPS LCREYVDALW PLVWKAGDRP
     GFVAEVQAMR RRVESLIPPA QAGRELKLGR GGLRDVEFSV QLLQLVHGRV DITLRTGGTL
     PGLLALSVGG YVGREDAATL AASYRFLRTV EHRLQLLRLR RTHLLPTDEV QLRWLARSLG
     YKPDHRGDAV AVLRAELALH TREVRRIHEK LFYRPLLSAV ARVPGEQLAL GSEAAGVWLR
     ALGFADPDGA LRHLAALTGG VSRSASMQRY LLPVVLQTLA SAADPDAGLL AYRQVSEALG
     GNQWFLRLLR DEGQVAERLA LLLGSSQYVA GLLTRTPEAL RLLARDEELV PRPAAALTSA
     WRQSVARAGD AAEGVRVLRG LRRTELLRVA CADLLGLLDV VGVGVALRDV AVATLEAGLD
     AAVRTWAADA KVPVDQVPVD LAVIGMGRLG GREMSYGSDA DVLFVHRVRE GADESRAAGA
     ANQIAHALRR LLAEPAPDPA FEVDANLRPE GRQGSLSRSL SAFAEYYQRW VSVWEVQALL
     RAEPVAGDAA LGRDFCALVD PLRWPAEGLT DAQVAEIRRI KARVESERLP RGADPATHTK
     LGRGGLADVE WTVQLLQLQH AHDHPALRVT PTVDALVALG EAGLLPTEDV DALRDAWERA
     SRARNAVFLV RGRPGDQLPR PGLELSGVAR ASGYPADADP GGFVDDYRRA ARHARSVVER
     VFYGRADD
//