ID A0A1G7VG31_9PSEU Unreviewed; 340 AA.
AC A0A1G7VG31;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=DNA-binding transcriptional regulator, LacI/PurR family {ECO:0000313|EMBL:SDG58765.1};
GN ORFNames=SAMN05216553_109215 {ECO:0000313|EMBL:SDG58765.1};
OS Lentzea fradiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=200378 {ECO:0000313|EMBL:SDG58765.1, ECO:0000313|Proteomes:UP000199623};
RN [1] {ECO:0000313|Proteomes:UP000199623}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3506 {ECO:0000313|Proteomes:UP000199623};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNCC01000009; SDG58765.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G7VG31; -.
DR STRING; 200378.SAMN05216553_109215; -.
DR OrthoDB; 4268837at2; -.
DR Proteomes; UP000199623; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:SDG58765.1};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..66
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 15..41
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 340 AA; 36135 MW; 9A0D5346ECC6C6D0 CRC64;
MTEIDRHRRP GPRIEEVARL AGVSKSTVSR VINGEQYVSA KARDAVHTAI THLKYSPNQA
ARSLAGSKAN AIALIVSEQG GRVLGDPFFA GVMRGVHAEL AGRHIQLLLM MSRPEDHNDL
LTYLAGGHVD GALLVSLHGD DPLPRKLQEL GVPVVVGGRP LAATTVPFVD SDNFTGGLDA
VRHLVSIGRH RIATVAGPRD MAAGLDRLSG WRRGLGEAKL PADLVAEADF TPESGAQAMA
NLLDRAPDID AVFVAADIIA IGALQVLHAR GRRIPQDVAV VGFDDSLLAS TATPPLTTVR
QDVEQLGRTM TWRLLGELAG EEGLPPSLLL PTSLVRRESA
//
