ID   A0A1G7VJ27_CHIFI        Unreviewed;       929 AA.
AC   A0A1G7VJ27;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE            EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN   ORFNames=SAMN04488121_105141 {ECO:0000313|EMBL:SDG59805.1};
OS   Chitinophaga filiformis (Myxococcus filiformis) (Flexibacter filiformis).
OC   Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC   Chitinophaga.
OX   NCBI_TaxID=104663 {ECO:0000313|EMBL:SDG59805.1, ECO:0000313|Proteomes:UP000199045};
RN   [1] {ECO:0000313|EMBL:SDG59805.1, ECO:0000313|Proteomes:UP000199045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 527 {ECO:0000313|EMBL:SDG59805.1,
RC   ECO:0000313|Proteomes:UP000199045};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC         in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|ARBA:ARBA00001412};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
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DR   EMBL; FNBN01000005; SDG59805.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G7VJ27; -.
DR   STRING; 104663.SAMN04488121_105141; -.
DR   Proteomes; UP000199045; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:SDG59805.1};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..929
FT                   /note="beta-galactosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011660862"
FT   DOMAIN          27..194
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          219..319
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
SQ   SEQUENCE   929 AA;  104475 MW;  F336F755AADCF70B CRC64;
     MNKHVKLILL VAMMAIHAAV PAQNRISLAG KWKFRIDRDD QGIKQQWYTQ QLKDSLKLPG
     AMQSQGYGDE PSVNTKWIGD RYEAFLKEDK YAPYRKDDNF KFPFWLTPKK YYMGAAWYQK
     VINIPSHWTG QHISLTLERC HWGTTVYADS QLIGADSSLA TPHVYDLSHL SPGKHTLTIR
     VDNRYLSEVG INAHSASDQT QGTWNGIAGD IVLEAGSPVF VKQVQVYPDI LNRNIQLKIV
     LGRTGNATSA GSLSISVDKL PALKQSFSKD DSSLSFTYPM GDHPALWDEF NPKLYQLTVQ
     LQTADKKSID SKKVSFGMRS VGTANSKITV NNHPIFLRGT LECAIFPLTG YPPTDTAAWA
     RIFRIIKAHG LNHMRFHSWC PPEAAFTAAD HAGVYLSVEV DCWARVGDGL SVDNFLYEES
     NRIIAAYGNH PSFLMMVPTN EPAGGKNRDP YLAAFVNYWK NKDKRRLYSA GSGWPAIAEN
     DYHVLPEPRI QAWGEGLNSV INAKAPNSQF NFKEKLKDNK PVVAHEIGQW CVYPDFTERK
     KYTGLLQARN FDIFYDFMKK EHLQSQAHDF LMASGKLQAL CYKADIEAGM RTDYAGYQLL
     DLHDFPGQGT ALVGILDPFW NSKPYFTPAA FHRFSSATVP LAVISKFTWK NSEVFTADVQ
     IAHFGKEQLK KIPVKWKITG NNKRVIANGV LSANLDWKND NPAGNISCKL SGISKAEKLN
     LEIIVDGLGA NDWDFWVYPD MVDVQTGSDI TVTDELTPAI SEKLQAGATV LLQLNNKITE
     KKGAAIKTGM SAIFWNTAWT EGQAPHTLGI LCDPSSPLFN DFPTEYHSNW QWWDIIHTAQ
     PMHLDNFPAE LKPSVQLIDT WFEARKLGIL FEARVGKGKI VVTSIDLQHD LDTRLAARQL
     YHSLLSYMQT KAFNPVVAVR PEQIQELYK
//