ID A0A1G8A3W8_9VIBR Unreviewed; 786 AA.
AC A0A1G8A3W8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=endopeptidase La {ECO:0000256|PROSITE-ProRule:PRU01122};
DE EC=3.4.21.53 {ECO:0000256|PROSITE-ProRule:PRU01122};
GN ORFNames=SAMN04488136_109126 {ECO:0000313|EMBL:SDH15553.1};
OS Vibrio xiamenensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=861298 {ECO:0000313|EMBL:SDH15553.1, ECO:0000313|Proteomes:UP000198854};
RN [1] {ECO:0000313|EMBL:SDH15553.1, ECO:0000313|Proteomes:UP000198854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10228 {ECO:0000313|EMBL:SDH15553.1,
RC ECO:0000313|Proteomes:UP000198854};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of proteins in presence of ATP.; EC=3.4.21.53;
CC Evidence={ECO:0000256|PROSITE-ProRule:PRU01122};
CC -!- SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01122}.
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DR EMBL; FNDD01000009; SDH15553.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8A3W8; -.
DR STRING; 861298.SAMN04488136_109126; -.
DR OrthoDB; 9758568at2; -.
DR Proteomes; UP000198854; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041699; AAA_32.
DR InterPro; IPR046844; Lon-like_helical.
DR InterPro; IPR008269; Lon_proteolytic.
DR InterPro; IPR027065; Lon_Prtase.
DR InterPro; IPR046843; LonB_AAA-LID.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR10046:SF46; ARCHAEAL LON PROTEASE; 1.
DR PANTHER; PTHR10046; ATP DEPENDENT LON PROTEASE FAMILY MEMBER; 1.
DR Pfam; PF13654; AAA_32; 1.
DR Pfam; PF05362; Lon_C; 1.
DR Pfam; PF20436; LonB_AAA-LID; 1.
DR Pfam; PF20437; LonC_helical; 1.
DR PRINTS; PR00830; ENDOLAPTASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS51786; LON_PROTEOLYTIC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU01122};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01122}; Reference proteome {ECO:0000313|Proteomes:UP000198854};
KW Serine protease {ECO:0000256|PROSITE-ProRule:PRU01122}.
FT DOMAIN 562..757
FT /note="Lon proteolytic"
FT /evidence="ECO:0000259|PROSITE:PS51786"
FT COILED 134..164
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 652
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
FT ACT_SITE 695
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
SQ SEQUENCE 786 AA; 88475 MW; 9BA217E6F8EE3053 CRC64;
MAIERLEAKQ LYHAAELEKL TSKSTKELAP IDEIVGQERA QKAVEFAMSI KEKGYNIYAI
GQNGLGKRTM ILRYLSRHQH DTDALFDWCY VANFDDIRTP KVLKLPVGVG SRLRQDIEKL
MTKLVQALPL AFDNEMYYSR ADKLKNQLAQ KQEAELESIS HEAKEQGISL TITTQGDYQF
VAMNGEELHT EESFDALSKK EQEAFSDKID ELEIKLRKMV RHLTEWEESY SEKIKKLNDD
VTLDVITHFI KQLKIDYNEH SEIKTYLTEL QKDIVENADI FLEESNEQAE IATASLDKKL
PRRYKVNVLV SRPDSEFPIV VEENPNYHSL FGYIETATFK GTVFTDFSLI RAGSLHKANG
GVLMMDAQKV LEQPYVWDGL KRALRSRQMS FTSLEKEVTL TGAVSLDPEP IPLDVKIILF
GDYRTYQLLQ HYDPEFRELF RVTADFEDEM KRTSDSELQY ARFIASVVHD SNMLHCDRKA
IARIIEHSSR ISGDQFKLSL HSAHIANLLR ESNYVAKQAN SNMIRASHVE EALSNQELRV
NRLRDSVMEG FINGTTLLRT SGSAIGQVNA LSVLATSEYM FGAPNRITAT TCYGDGDVID
IERSVDLGGS IHSKGVMILT AYLSSVFGKT ARVPLTTTIT FEQSYGGVDG DSASMAEFCA
VVSAFAKQPN RQDIAITGSM NQFGEAQPIG GVNEKIEGFF DVCMIKGRSN EQGVIIPRSN
QHNLMLRPDI VKAVERGEFN IWAIDHVTEA IELFTGKQAG VASEEGSYPI DSIFGIAQAK
LNALRK
//
