ID A0A1G8AGM9_9PSEU Unreviewed; 534 AA.
AC A0A1G8AGM9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612};
DE EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612};
GN ORFNames=SAMN05216553_117185 {ECO:0000313|EMBL:SDH20155.1};
OS Lentzea fradiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=200378 {ECO:0000313|EMBL:SDH20155.1, ECO:0000313|Proteomes:UP000199623};
RN [1] {ECO:0000313|Proteomes:UP000199623}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3506 {ECO:0000313|Proteomes:UP000199623};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|RuleBase:RU000612};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|RuleBase:RU000612}.
CC -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|RuleBase:RU000612}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNCC01000017; SDH20155.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8AGM9; -.
DR STRING; 200378.SAMN05216553_117185; -.
DR UniPathway; UPA00109; UER00181.
DR Proteomes; UP000199623; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR001672; G6P_Isomerase.
DR InterPro; IPR046348; SIS_dom_sf.
DR PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF00342; PGI; 1.
DR PRINTS; PR00662; G6PISOMERASE.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 2.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432,
KW ECO:0000256|RuleBase:RU000612};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|RuleBase:RU000612};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU000612}.
SQ SEQUENCE 534 AA; 55683 MW; 894D53C1B3947A14 CRC64;
MTSVDIVRSP NADQVSIIAA DLVADSVPSK LTAQDPTLWG PEAESEASIR LSWTTLHETS
RALLPELKAL REDLHAEGVD RVVLAGMGGS SLAPEVITRT QGVPLVVLDT TDPAQVADAL
AGDLQRTVIV VSSKSGGTVE TDSHRRIFEK AFTDAGIDAA SRIVVVTDPG SPLQSASEEA
GYRKVFLADP NVGGRYSALT AFGLVPSYLA GADVESLLDE AAEVAKIVSQ DSAENPAVQL
AAIFGAAHAN GAEKIVFADT GSGIKGFGDW AEQLIAESTG KNGTGLLPVV VEGPGAEGFV
NARSDATTVA IGPATGSATV AVEGKLGAQF LLWEYATALV GRVLGINPFD QPDVEAAKKA
ARALLDAPAV AATEPSFVDG PVEAHGTDWA PRKVSTVAEA LAALVEVAPD HGYISVQAYL
DRIDDASFEL LRAEIAKRTH LQTTFGWGPR FLHSTGQYHK GGHQNGVFVQ ITGESGDDLE
VPGRPYTLAQ LQLAQALGDG QVLAEHGRPV LRLHLTDRVA GLAQLVEAVQ EDGS
//
