ID A0A1G8CD40_9PSED Unreviewed; 291 AA.
AC A0A1G8CD40;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=3-hydroxyisobutyrate dehydrogenase {ECO:0000313|EMBL:SDH43362.1};
GN ORFNames=SAMN05216272_101521 {ECO:0000313|EMBL:SDH43362.1};
OS Pseudomonas panipatensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=428992 {ECO:0000313|EMBL:SDH43362.1, ECO:0000313|Proteomes:UP000199636};
RN [1] {ECO:0000313|EMBL:SDH43362.1, ECO:0000313|Proteomes:UP000199636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 7469 {ECO:0000313|EMBL:SDH43362.1,
RC ECO:0000313|Proteomes:UP000199636};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNDS01000001; SDH43362.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8CD40; -.
DR STRING; 428992.SAMN05216272_101521; -.
DR OrthoDB; 9786703at2; -.
DR Proteomes; UP000199636; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 2..155
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 166..283
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 169
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 291 AA; 30083 MW; 3F182D54DA846E81 CRC64;
MNIGFLGLGG MGAAMAANLV KAGHQVRVWN RSAAALEPLL ALGATAAADP VAAFDGEVVI
SMLADDAATR AVIFDSGALA SAKPGLIHLG MATLSVDLVG ELVARHRERG VVYVAAPVFG
RTDVAAAGKL NILAAGPAQA IATVQPLLDA MGQKTWPLGE DPLRAAVVKI AGNFMIASAI
EAMGESSALV KRFGVEPAQL LEIMSGTLFD APVYRNYGAQ IAAQRYEPAA FRLVLGLKDV
GLALSAGQGR HVPLPFASVL RDNLLEAIAQ GDGERDWAAL AQVAMRRSGQ D
//
