ID   A0A1G8CDW1_9BURK        Unreviewed;       664 AA.
AC   A0A1G8CDW1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC {ECO:0000313|EMBL:SDH43625.1};
GN   ORFNames=SAMN05444748_101343 {ECO:0000313|EMBL:SDH43625.1};
OS   Variovorax sp. OV700.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=1882826 {ECO:0000313|EMBL:SDH43625.1, ECO:0000313|Proteomes:UP000199505};
RN   [1] {ECO:0000313|Proteomes:UP000199505}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OV700 {ECO:0000313|Proteomes:UP000199505};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNDR01000001; SDH43625.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8CDW1; -.
DR   STRING; 1882826.SAMN05444748_101343; -.
DR   OrthoDB; 9803111at2; -.
DR   Proteomes; UP000199505; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        49..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          290..579
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
FT   REGION          638..664
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   664 AA;  72034 MW;  B9997088D63B6B7A CRC64;
     MIDRMAQPML ALPRPVKRVL ALLVDAGLCV LCVWLAFSLR YERWIELTGV HWLAVAGAIM
     LALPLFVVSG LYRAIFRYAG SAALMAVVHA CSLFSVGYVL IFTAFGVEGI PRTVGLLVPA
     LLLFTVGASR LVARYWLGGL YTQVLRGKAL PQVVIYGAGE AGRQLAAALA HSPEMVVRRF
     VDDSVQLQGS TLNELPIDPP SWLEAHAAAE GITDVLLALP SVSYGRRAQI LNELLSLHLR
     VRTLPGMADL AQGRVQVKDL MEVDIEDLLG RDPVAPVDDL LNRHVRGKVV LVTGAGGSIG
     SELCRQIAQL RPSVLLLVEW SEYALYAIHR ELEQEAPALS VVPLLASVCD GARMRQIMSV
     WRPNTIYHAA AYKHVPLVEH NPVEGLINNT LGTLTAALAA RDNGVGQFVL VSTDKAVRPT
     NIMGASKRLA EMTLQGLAQQ KSRTCFSMVR FGNVLGSSGS VVPLFRQQIE AGGPITLTHE
     DITRYFMTIP EAAQLVIQAG AMAEGGDVFV LEMGSPVRII DLARRLVELS GRTVRDARNP
     EGDIELLITG LRPGEKLYEE LLIGDNAMPT AHPRVMKAHE ACPPWAELAT QIDELRTLLA
     RNDVPGLKRK LQQLLGGYRP HAEVVDWVHL ERERQSGTLP EHVASTPSAA APVATVSPSA
     LAPI
//