ID A0A1G8CGI1_9BURK Unreviewed; 369 AA.
AC A0A1G8CGI1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=SAMN05444748_101354 {ECO:0000313|EMBL:SDH44000.1};
OS Variovorax sp. OV700.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1882826 {ECO:0000313|EMBL:SDH44000.1, ECO:0000313|Proteomes:UP000199505};
RN [1] {ECO:0000313|Proteomes:UP000199505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV700 {ECO:0000313|Proteomes:UP000199505};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR EMBL; FNDR01000001; SDH44000.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8CGI1; -.
DR STRING; 1882826.SAMN05444748_101354; -.
DR Proteomes; UP000199505; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513}.
FT DOMAIN 7..354
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 369 AA; 40808 MW; 476A1F12547B08A1 CRC64;
MAPLVKHLQT LPAFETRVCV TAQHREMLDQ VLSLFEITPD FDLNLMKPGQ DLTDITAGVL
RGLKETLTQW RPDAMLVHGD TSTTFAATLA AFYQRIPVGH VEAGLRTGNL YSPWPEEANR
KLTSVLGHWH FAPTDASRDN LLAEGVAPDT VHVTGNTVID SLLQVRDRIR DDMALQQRFA
EQFRFIDPAK RLVLVTGHRR ENFGGGFERI CEALGRIART HADVQVVYPV HLNPQVQEPV
RRLLGNVGNV HLIEPLDYLP FVYLMDRSTL ILTDSGGIQE EAPSLGKPVL VMRDTTERPE
AVAAGTVKLV GTDIERIVAQ AHVLLTDAAA YQIMAHAHNP YGDGRACQRI AQTLSLAEKT
RSVSQSAIA
//
