ID A0A1G8CZ25_9PSEU Unreviewed; 346 AA.
AC A0A1G8CZ25;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=3-oxoacyl-[acyl-carrier-protein] synthase-3 {ECO:0000313|EMBL:SDH50755.1};
GN ORFNames=SAMN05216553_12537 {ECO:0000313|EMBL:SDH50755.1};
OS Lentzea fradiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=200378 {ECO:0000313|EMBL:SDH50755.1, ECO:0000313|Proteomes:UP000199623};
RN [1] {ECO:0000313|Proteomes:UP000199623}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3506 {ECO:0000313|Proteomes:UP000199623};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Antibiotic biosynthesis. {ECO:0000256|ARBA:ARBA00004792}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. FabH family.
CC {ECO:0000256|ARBA:ARBA00008642}.
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DR EMBL; FNCC01000025; SDH50755.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8CZ25; -.
DR STRING; 200378.SAMN05216553_12537; -.
DR OrthoDB; 7055207at2; -.
DR Proteomes; UP000199623; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00827; init_cond_enzymes; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013751; ACP_syn_III_N.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR34069; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 3; 1.
DR PANTHER; PTHR34069:SF2; BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III; 1.
DR Pfam; PF08545; ACP_syn_III; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194}.
FT DOMAIN 109..188
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08545"
FT DOMAIN 250..339
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
SQ SEQUENCE 346 AA; 37158 MW; 31704703667C2878 CRC64;
MRWNDLYIAG VGTYLPEQVE TVDDAIAAGR YTEEKKAMNG YRELRVAAPG ETGPVMAVKA
GVQAVERSGL NPLDFGLTVH ASLSHQGLDL WTPASYVQAG TVGGSGPAFE VKQGCNGFMA
AVDLAASYLS AHRDSTAALV TAGDAFHLPY FDRWASEEQN VNGDGAGAFV LSNRSGFARV
RSIHSHSDST LEQMSRGYAE WTTGPFADGR TLQLNSGVED FLRNGDVDLD DMIARIGGGV
RHSLKMALYE ADVELQDARF FLHQQLAETI VTHGICGLLG VDRASTTYDW AKQYSMVGTA
DLAIGLDHVL ADRDPKPGDL VVLQSSGAGY VWTAAVIEIL EVPSWV
//
