ID A0A1G8D5Q0_9MICO Unreviewed; 519 AA.
AC A0A1G8D5Q0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SAMN04489810_3258 {ECO:0000313|EMBL:SDH53056.1};
OS Microbacterium pygmaeum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=370764 {ECO:0000313|EMBL:SDH53056.1, ECO:0000313|Proteomes:UP000199009};
RN [1] {ECO:0000313|EMBL:SDH53056.1, ECO:0000313|Proteomes:UP000199009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23142 {ECO:0000313|EMBL:SDH53056.1,
RC ECO:0000313|Proteomes:UP000199009};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; LT629692; SDH53056.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8D5Q0; -.
DR STRING; 370764.SAMN04489810_3258; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000199009; Chromosome i.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06568; GH20_SpHex_like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 2.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000199009}.
FT DOMAIN 14..135
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 138..320
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT DOMAIN 329..477
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 319
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 519 AA; 55515 MW; B91AF81D52A7531F CRC64;
MKSADQNDVI VPTIAIVPAP ARIEVLASPA FRLTPDVQIA GDPDAGAALA ALIQARTGDR
SVLAHGRAPI TVRIEAGGLE PGGSAESYRL EVDEESVSLV GTDAAGLFYG VQTLAQLITR
QGEAFVIPAV RIEDAPRFAY RGVMLDVARH FHSAETVEAY VDRAAALKFN VLHLHLSDDQ
GWRIQLDSRP ELTDVASGSS VGGDPGGFYT KADYARIIDH AASRHMIVVP EIDLPGHTHA
VGLAYPQLAE APVLSDHIRE VAEQHGGALP TPGVPYDGMA VGFSSLRIHD ERTYDFVTDV
LTELAAMTPG PYLHVGGDEA LGTDPEDFAL FMARVTAIAV SLGKTPVTWH EAGDAEGIAP
TTIGQYWGFL TPTDGMDEKA RGFVAHGSRV ILSPADAIYL DMKYDAGNPL GLTWARGVTS
VERAYSWEPG TLLDGIGEAD ILGVEAPMWT ETIRTLDDID EMAFPRIAAA AEAAWSPATT
ASELRTWESF RERVGGLGPL WKSLGFGLPH SDELTWATR
//
