ID   A0A1G8EJ22_9MICC        Unreviewed;       301 AA.
AC   A0A1G8EJ22;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=4-hydroxy-tetrahydrodipicolinate synthase {ECO:0000313|EMBL:SDH69792.1};
GN   ORFNames=SAMN04488693_102135 {ECO:0000313|EMBL:SDH69792.1};
OS   Arthrobacter subterraneus.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Arthrobacter.
OX   NCBI_TaxID=335973 {ECO:0000313|EMBL:SDH69792.1, ECO:0000313|Proteomes:UP000199258};
RN   [1] {ECO:0000313|EMBL:SDH69792.1, ECO:0000313|Proteomes:UP000199258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NP_1H {ECO:0000313|EMBL:SDH69792.1,
RC   ECO:0000313|Proteomes:UP000199258};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
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DR   EMBL; FNDT01000002; SDH69792.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8EJ22; -.
DR   STRING; 335973.SAMN04488693_102135; -.
DR   OrthoDB; 9778880at2; -.
DR   Proteomes; UP000199258; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   InterPro; IPR020625; Schiff_base-form_aldolases_AS.
DR   PANTHER; PTHR12128:SF72; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS00666; DHDPS_2; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199258};
KW   Schiff base {ECO:0000256|ARBA:ARBA00023270}.
FT   ACT_SITE        134
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   ACT_SITE        162
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
SQ   SEQUENCE   301 AA;  31379 MW;  D4D83C9083955997 CRC64;
     MVFTGVVAYP LTPFHADGGV NSAELKLLVD RLALSGIDSI TVLGSSGSFA YLDADERRQV
     LADAVEAAGG RVPVAAGISA VATREVVAGA RAAEQVGADG VVLSPVSYLP LTDDELIVLV
     EEVAAATTLP ICLYNNPSTT QFSIDVDLVA RMAHVPTLVA FKDTAATPAE FAERAARLRE
     VLDRPISHGA SSDPLLATGE VAADAWHTGL AALLPASYLA FRAAVLDGDA ARISAERSRL
     VPVVQAVHRL RKLSGLHALG RACGIDAGDP RHPLLPIAGS EQRDLARLAE AFDDVEDGVL
     R
//