ID A0A1G8FCX1_9BRAD Unreviewed; 444 AA.
AC A0A1G8FCX1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=C4-dicarboxylate transport protein {ECO:0000256|HAMAP-Rule:MF_01300};
GN Name=dctA {ECO:0000256|HAMAP-Rule:MF_01300};
GN ORFNames=SAMN05216338_1013130 {ECO:0000313|EMBL:SDH80000.1};
OS Bradyrhizobium sp. Rc2d.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=1855321 {ECO:0000313|EMBL:SDH80000.1, ECO:0000313|Proteomes:UP000198770};
RN [1] {ECO:0000313|EMBL:SDH80000.1, ECO:0000313|Proteomes:UP000198770}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Rc2d {ECO:0000313|EMBL:SDH80000.1,
RC ECO:0000313|Proteomes:UP000198770};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC succinate, fumarate, and malate across the membrane.
CC {ECO:0000256|HAMAP-Rule:MF_01300}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01300};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01300}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148,
CC ECO:0000256|HAMAP-Rule:MF_01300}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01300}.
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DR EMBL; FNCU01000013; SDH80000.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8FCX1; -.
DR STRING; 1855321.SAMN05216338_1013130; -.
DR OrthoDB; 9766690at2; -.
DR Proteomes; UP000198770; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006835; P:dicarboxylic acid transport; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR HAMAP; MF_01300; C4_dicarb_transport; 1.
DR InterPro; IPR023954; C4_dicarb_transport.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF1; AEROBIC C4-DICARBOXYLATE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01300};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01300};
KW Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|HAMAP-Rule:MF_01300};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01300};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01300};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01300}.
FT TRANSMEM 22..41
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 93..115
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 164..183
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 195..223
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 229..255
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
SQ SEQUENCE 444 AA; 46911 MW; A53B403225736562 CRC64;
MTTTTMAEAP VAPPAAKPWY KILYVQVLIA IVLGAIVGWL WPQLATNEWI KALGDGFIKL
IKMVIAPIIF CTVVSGIAHI QDAKKVGRIG VKALVYFEVV STFALVIGLI IGNLVKPGAG
FGSGAASEAA VANYAKQAAG QKSVDFVLHI IPDTVVGAFA QGEILQVLLF SVLFGFAIMS
LGERGHTIRS FIDDAAHAVF GVISIVMRAA PIGAFGAMAY TIGKFGTGAI LNLVGLIATF
YLTAALFVFV VLGIIARVAG FSIFKFLAYI KDELLIVLGT SSSESALPSL MEKLERLGCS
KSVVGLVVPT GYSFNLDGTN IYMTLATLFI AQALGYDLSF SQQLTILVVA MLTSKGASGI
TGAGFITLAA TLAVVDPRLV PGMAIVLGID KFMSECRALT NLCGNGVACV IVAWWERELD
RDKLNANLSK QIDPTDMETA ITTD
//
