ID A0A1G8H5C0_9MICO Unreviewed; 452 AA.
AC A0A1G8H5C0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=MFS transporter, MHS family, alpha-ketoglutarate permease {ECO:0000313|EMBL:SDI01828.1};
GN ORFNames=SAMN04489720_3221 {ECO:0000313|EMBL:SDI01828.1};
OS Agrococcus jejuensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Agrococcus.
OX NCBI_TaxID=399736 {ECO:0000313|EMBL:SDI01828.1, ECO:0000313|Proteomes:UP000198822};
RN [1] {ECO:0000313|EMBL:SDI01828.1, ECO:0000313|Proteomes:UP000198822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22002 {ECO:0000313|EMBL:SDI01828.1,
RC ECO:0000313|Proteomes:UP000198822};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LT629695; SDI01828.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8H5C0; -.
DR STRING; 399736.SAMN04489720_3221; -.
DR OrthoDB; 8953821at2; -.
DR Proteomes; UP000198822; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17367; MFS_KgtP; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR43528; ALPHA-KETOGLUTARATE PERMEASE; 1.
DR PANTHER; PTHR43528:SF1; ALPHA-KETOGLUTARATE PERMEASE; 1.
DR Pfam; PF00083; Sugar_tr; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022847}.
FT TRANSMEM 56..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..428
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 452 AA; 48646 MW; CD1C4FA8EC90A1AE CRC64;
MSTTTHAPAS LRRSVSNTLK GSAGNLVEWF DVYVYSVFAS YFESQFFAED DQNSGIYIWA
IFAVTFLMRP LGSWFFGRLA DRRGRRYALT VSVSLMAACS FVIAITPTAA VIGAGAAVIL
VLCRLAQGFA TGGEYGTSAT YMSEAAIPGR RGFLSSFHYV TLVGGHVLAQ ATLLVMVLTL
DTTAISEWGW RVAFGIGGVA AVVVFWLRRT MDESLTSDTL DAVKTGESRQ SGSMKELLVH
QWRPLLLCFL VTMGGTVAFY TYSVNGPNIV KGAFAGDSVV TGTVINLIAL TILMLLQPLG
GWISDIVGRK TLLVFFGVGG VLYTWFLLTW LPQQTNAVAA FAILVGGFVI LTGYTSINAV
VKAELFPTHI RALGVGFGYA LANSMFGGTA PLLYTAANGA GQVPLFIGYV TIAIGASLVV
YVLFLKNKGQ NWLDDEHGMR ERIAERVGAR KD
//
