ID A0A1G8HGY3_9MICC Unreviewed; 547 AA.
AC A0A1G8HGY3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=SAMN04488693_105202 {ECO:0000313|EMBL:SDI05937.1};
OS Arthrobacter subterraneus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=335973 {ECO:0000313|EMBL:SDI05937.1, ECO:0000313|Proteomes:UP000199258};
RN [1] {ECO:0000313|EMBL:SDI05937.1, ECO:0000313|Proteomes:UP000199258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NP_1H {ECO:0000313|EMBL:SDI05937.1,
RC ECO:0000313|Proteomes:UP000199258};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
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DR EMBL; FNDT01000005; SDI05937.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8HGY3; -.
DR STRING; 335973.SAMN04488693_105202; -.
DR OrthoDB; 3713880at2; -.
DR Proteomes; UP000199258; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18029; DEXHc_XPB; 1.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000199258}.
FT DOMAIN 190..344
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 398..547
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 547 AA; 60616 MW; 7596CD2AE500482D CRC64;
MPNGPLIVQS DKTILLEVDH EQATEARHAI AAFAELERAP EHVHSYRLTP LGLWNARAAG
LDAEQVLDTL LKYSRFPVPH ALLVDIEETM SRYGRLRLEK DAQHGLVLRT TDYPVLEEVL
HAKKIEPLLG PRIDGETVVV HSSQRGQLKQ LLLKLGWPAE DLAGYVDGTP HPIMLNEDGW
TLRPYQKLAT ENFWAGGSGV VVLPCGAGKT LVGAAAMATS STTTLILVTN TVSARQWKDE
LLKRTSLTEE EIGEYSGSVK EVRPVTIATY QVLTLRRGGL YPHLELLDAN DWGLIVYDEV
HLLPAPIFRM TADLQARRRL GLTATLVRED GREGEVFSLI GPKRYDAPWK DIEAQGYIAP
ADCVEVRVDL PRDERVAYAM ADDGDKYRLC ATSETKTSVV EKLVAAHKGE QLLVIGQYID
QLDELGARLD APIIKGETSV KERQRLFNAF RAGELNTLVV SKVANFSIDL PEASVAIQVS
GSFGSRQEEA QRLGRLLRPK SDGRAARFYT VVARDTLDQD FAAKRQRFLA EQGYAYTILD
AADIPTP
//
