ID A0A1G8HYW0_9MICC Unreviewed; 1029 AA.
AC A0A1G8HYW0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Peptidase inhibitor I9 {ECO:0000313|EMBL:SDI11711.1};
GN ORFNames=SAMN04488693_10671 {ECO:0000313|EMBL:SDI11711.1};
OS Arthrobacter subterraneus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=335973 {ECO:0000313|EMBL:SDI11711.1, ECO:0000313|Proteomes:UP000199258};
RN [1] {ECO:0000313|EMBL:SDI11711.1, ECO:0000313|Proteomes:UP000199258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NP_1H {ECO:0000313|EMBL:SDI11711.1,
RC ECO:0000313|Proteomes:UP000199258};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; FNDT01000006; SDI11711.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8HYW0; -.
DR STRING; 335973.SAMN04488693_10671; -.
DR Proteomes; UP000199258; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.120.380; -; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF468; SUBTILISIN-LIKE PROTEASE SBT3.18; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000199258};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 44..139
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 172..649
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 453..522
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 701..793
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT REGION 1006..1029
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 181
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 279
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 605
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 1029 AA; 104480 MW; 363A8BE1BC883842 CRC64;
MVGLPLILGS MSAVPAAAVP AGPTATQQIQ PVKKVDPGNY PDGRYIVVLN EEPAAMYDGG
VPGIEATKPE KGEKLSEKKD FQKYKSHLEQ KQQAVAGEKG VAIKRSYTAA LNGFSAKLTS
DQAVELAKDP GVRMVAPDVE NAPDDYSSLD ILNLRGEGGA WNTQFGGEAN AGAGTVVGVI
DTGYTPSSPF FQGTEVVKLK KGEQPQVGQP YRAKGGIAML KSDGTTFLGE CEVGVRFSGT
ECNSKVLAAQ YFSEDFEEYV PKANRAPEEV LSPIDVDSHG THTASTAVGN SNVTQTVAGR
DFGKSSGVAP AAKLSVYKVC WADNDPNTGG CYSSASIAAI NQAVLDGVDV LNYSISGSAT
TTTDPVSLAF LGAASAGVFV SASAGNSGPT ASTVNHGAPW VTTVAASTFS HALQGTAEFA
DGTKFRGASI MSAGVPASPV VLSANAAAAG AKDGDLCAPN SLDPTRVAGK IVVCDRGVYD
RVAKSAEVAR TGGVGMILVN LTDSSMDTDK HSVPTIHVNT PASLELKEKV AANPDMLVAL
VDEDTTGEPL PPVPQIAGFS SRGPLLATGS DLLKPDVAAP GVAVLAGVSP IGTGGDEFGF
LSGTSMAAPH VAGVGALILA KNPAWSPAAV KSAMMTTADP VKNAQGGVDG DVFATGAGQV
DPISVLNPGL VYDAGRIEYL QFVEGTGYAD VKGVEGIDAK NMNVPSFAVG NLTGKTTVTR
TVTALTPGTY TATANVPGVN VKVTPSVLNF TKAGEKQTFE VTFENAEAQL GKFAKGSLVW
EGQGKVVASP VAVRPQSVVA PSQVAFTSEG PDGSGTIPVT SGTNAPVSMT LQGLSKANSS
PLSLVPGPVV VENNASNYVT EVTVPKDTPF ASLSVLSADP GADFDLFVFD PNGRLYQVAT
ASASETLNLQ NPVPGVYKAI VNLYASPNGQ ATAATFDAAI LGADEGNASI APNPLELANG
ESGEVTLNWA GLEPGSYVGR VTYAGSTAVT FVSVVVDGAG VAAPTAVSPT GGANKLPSAD
GDSTPTNGQ
//
