ID A0A1G8I6U9_9MICC Unreviewed; 1034 AA.
AC A0A1G8I6U9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
DE AltName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230};
GN ORFNames=SAMN04488693_106159 {ECO:0000313|EMBL:SDI14695.1};
OS Arthrobacter subterraneus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=335973 {ECO:0000313|EMBL:SDI14695.1, ECO:0000313|Proteomes:UP000199258};
RN [1] {ECO:0000313|EMBL:SDI14695.1, ECO:0000313|Proteomes:UP000199258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NP_1H {ECO:0000313|EMBL:SDI14695.1,
RC ECO:0000313|Proteomes:UP000199258};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; FNDT01000006; SDI14695.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8I6U9; -.
DR STRING; 335973.SAMN04488693_106159; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000199258; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR004199; B-gal_small/dom_5.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032312; LacZ_4.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR Pfam; PF02929; Bgal_small_N; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF16353; LacZ_4; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01038; Bgal_small_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000199258}.
FT DOMAIN 743..1031
FT /note="Beta galactosidase small chain/"
FT /evidence="ECO:0000259|SMART:SM01038"
SQ SEQUENCE 1034 AA; 114140 MW; 38EEBCA2BCD8BC25 CRC64;
MIPSRSEVAA YVTDTAPGGG SRLPARSWLR SDAPSLTLDG EWRFRRLRGV PGTPGGRGFL
PQSEAPESMV TEEYDDAAWD TLPVPAHWVL EGDGAYGRPI YTNVQFPFPC DPPFVPDENP
TGDYRRTFEI PEEWMKAERI VLRFEGVESR YKVWVNGEEI GWGAGSRLAQ EFDVTSAIRT
GSNTIAVRVH QWSASSYIED QDQWWLPGIF RSVTLQARPA GGIEDVWLRT GYHDGIGTLD
PEVSAPASSF PIRLTIPELG IDVEWTKPAD VAPLEVGSVQ AWSAEIPQLY DATVASTTEA
VELRIGFRTV EIVGDRFLVN GRTVTFHGVN RHETHPEQGR VFDEDFARED LLLMKRFNVN
AIRTSHYPPH PRLLDLADEL GFWVILECDI ETHGFERHDW VGNPSDDPAW HEAYLDRIER
TVERDKNHPS IIMWSLGNES GTGGNLAAMS AWVHARDAGR PVHYESDYAG AYTDVYSRMY
STVPETETIG RDGDTSPLLG CSPAESARQR TKPFILCEYA HAMGNGPGNL SLYERLVDRY
PRLHGGFVWE WRDHGLRTRT PDGTEYFAYG GDFGEEIHDG NFVLDGLVLS DSTPTPGLYE
FKSVVAPVRI SFESPEGERA GSKPLLRVRN LRHTASTADF TFRWRLEDNG EKVASGELSI
LGLHGGPLEA GEEAVLGLPT TGEGCQGEAW LTVEAVLAHS TAWAEEGHEI TAAQLQLAER
PAPARPRPVQ GPLTPATATG TLELGPAVFD DGWLVALAGL AVDGPRLELF RAPTDNDRGR
FVGSYIDSDP WAPDIHGVPG NGRPGASSAE RWNSAGLNRM HGRVQSVETK RDAVRVRTRY
AAADHARHVT VDETWQLDGQ NLWLRVDLLP SSGWNGVWPR AGVRFGLPDT VDGVSWFGLG
PHESYPDSLQ AALVGRYQSG IEELPVKYGR PQETGHRSGL RSLNLRTGAH PWLRIDSFAD
SQGRLPGFTL SRHTAQELAT AAHPHELPAS ERAWLYLDAA QHGLGTRSCG PDVWPTEALA
PEARSINLLI SVAE
//
