ID   A0A1G8ICY3_9BACI        Unreviewed;       482 AA.
AC   A0A1G8ICY3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SDI16775.1};
GN   ORFNames=SAMN05216352_105141 {ECO:0000313|EMBL:SDI16775.1};
OS   Alteribacillus bidgolensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Alteribacillus.
OX   NCBI_TaxID=930129 {ECO:0000313|EMBL:SDI16775.1, ECO:0000313|Proteomes:UP000199017};
RN   [1] {ECO:0000313|EMBL:SDI16775.1, ECO:0000313|Proteomes:UP000199017}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P4B,CCM 7963,CECT 7998,DSM 25260,IBRC-M 10614,KCTC 13821
RC   {ECO:0000313|Proteomes:UP000199017};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FNDU01000005; SDI16775.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8ICY3; -.
DR   STRING; 930129.SAMN05216352_105141; -.
DR   Proteomes; UP000199017; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199017};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        77..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        106..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        191..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        219..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        246..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        310..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        353..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        396..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        423..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   482 AA;  52399 MW;  A5D5F88D45FFE833 CRC64;
     MDTWLTMDTW LGDVVDLSNK ILWTYILVGL LLFLGVFFTV KTRFVQFRMV KEMVMLLVQG
     TDRTDFKKKK GTTPFQAFTI STAARVGTGN LAGVALAITA GGPGAIFWMW MIALVGAATG
     FVESTLAQMY KVKDKDGFRG GPAYYMEKAL GMRWMGVLFA ILITLCFGLI FNAVQTNTIS
     QAFTGAYDIS PFWVGSTIAV LIGIIIFGGI RRIAVVSEFV VPFFAIIYII VSLVVMFFNI
     GALPEVFSLI VSNAFGLQEI AGGGLGAAIM NGVQRGLFSN EAGMGSAPNA AATAHVSHPV
     KQGLVQTLGV FTDTLIICSS TAFLIILAGV HTSSESDGIQ LTQLALNTHL GDWAQVFVTI
     AIFFFAFSSL LGNYYYGEAN IEFISENPAY VQAFRVAFLI MVMVGAMSEL EIIWALADVF
     MGSMALVNLI AAALLTKIAV SALEDYQQQR KLGKDPVFYK DSIPGLNNIE AWDKKPKRSE
     QE
//