ID A0A1G8JV96_9BACL Unreviewed; 577 AA.
AC A0A1G8JV96;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Endonuclease G {ECO:0000313|EMBL:SDI35149.1};
GN ORFNames=SAMN04487975_11545 {ECO:0000313|EMBL:SDI35149.1};
OS Planococcus glaciei.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Planococcus.
OX NCBI_TaxID=459472 {ECO:0000313|EMBL:SDI35149.1, ECO:0000313|Proteomes:UP000183022};
RN [1] {ECO:0000313|Proteomes:UP000183022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.6846 {ECO:0000313|Proteomes:UP000183022};
RA Varghese N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNDC01000015; SDI35149.1; -; Genomic_DNA.
DR RefSeq; WP_074511178.1; NZ_FNDC01000015.1.
DR AlphaFoldDB; A0A1G8JV96; -.
DR STRING; 459472.SAMN04487975_11545; -.
DR eggNOG; COG1864; Bacteria.
DR eggNOG; COG3591; Bacteria.
DR OrthoDB; 9770276at2; -.
DR Proteomes; UP000183022; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00091; NUC; 1.
DR Gene3D; 3.40.570.10; Extracellular Endonuclease, subunit A; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001604; DNA/RNA_non-sp_Endonuclease.
DR InterPro; IPR044929; DNA/RNA_non-sp_Endonuclease_sf.
DR InterPro; IPR020821; Extracellular_endonuc_su_A.
DR InterPro; IPR044925; His-Me_finger_sf.
DR InterPro; IPR040255; Non-specific_endonuclease.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR PANTHER; PTHR13966:SF5; ENDONUCLEASE G, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13966; ENDONUCLEASE RELATED; 1.
DR Pfam; PF01223; Endonuclease_NS; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR SMART; SM00892; Endonuclease_NS; 1.
DR SMART; SM00477; NUC; 1.
DR SUPFAM; SSF54060; His-Me finger endonucleases; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:SDI35149.1};
KW Hydrolase {ECO:0000313|EMBL:SDI35149.1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR640255-2};
KW Nuclease {ECO:0000313|EMBL:SDI35149.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 354..558
FT /note="DNA/RNA non-specific endonuclease"
FT /evidence="ECO:0000259|SMART:SM00892"
FT DOMAIN 355..558
FT /note="Extracellular Endonuclease subunit A"
FT /evidence="ECO:0000259|SMART:SM00477"
FT ACT_SITE 417
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR640255-1"
FT BINDING 451
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR640255-2"
SQ SEQUENCE 577 AA; 64608 MW; 82BCBEDBB1F7B125 CRC64;
MQTSKLAHIE QQALKRYLQF NAEKQSAAAT QDAQSRMMSR SSIINVHDNL AMERIINRSD
LFPIAHLQAG LDVSKAVCRI SLRNRSGQIE GYGTGFMVAP SLLLTNNHVL DAFDAAQYAV
AEFNYEDDVN FMPKEIVSFR LAPEQLFITD IGLDFTLVAV HEVDTEGVRL ADFGYLPLLP
QTGKVLEGEY VSIIQHPKGG PKAVTLRENE VKSISSDYVH YVSDTEPGSS GSPVFNDQWV
VVSLHHAGIP HPDNEGEWIA NEGIRISSIL RFLRLRRNGV EDGAGRKLLD ALLAAPDSLV
PAMEVGTLEA EWYSGAAGYN SAFLGLDAEV PLPLLNESQQ TDVMGTEDGK KILDYTHFSI
VMSRSRKLAF YSAVNIDGTQ LIEVRRENDK WYFDPRIPKE FQVGPEVYKN NDIDRGHLTR
RQDPNWGIDA VKANEHTFHF TNCAPQHKNF NQKTWLDLEN YILDNAGDYG LKVTVFTGPV
FRESDVVYRG CQIPSQFWKV AVLRKEDGTL SATAYLQSQE NLLGDLEFVY GDFQTYQVPV
TQIEELTGLG FGELRKFDPL AETAVQVVIA GREDIRL
//
