ID A0A1G8KCV1_9BACI Unreviewed; 659 AA.
AC A0A1G8KCV1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:SDI41238.1};
GN ORFNames=SAMN04488123_10228 {ECO:0000313|EMBL:SDI41238.1};
OS Natribacillus halophilus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Natribacillus.
OX NCBI_TaxID=549003 {ECO:0000313|EMBL:SDI41238.1, ECO:0000313|Proteomes:UP000198853};
RN [1] {ECO:0000313|EMBL:SDI41238.1, ECO:0000313|Proteomes:UP000198853}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21771 {ECO:0000313|EMBL:SDI41238.1,
RC ECO:0000313|Proteomes:UP000198853};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNEN01000002; SDI41238.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8KCV1; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000198853; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd05943; AACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198853}.
FT DOMAIN 40..96
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 100..472
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 542..617
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 659 AA; 74587 MW; 5A4E41218FC14CE9 CRC64;
MPVKEGELLW EPSQAFINQS NLAHYMKWLE DKKGLAFNDY QQLWEWSVNN VEDFWETQWE
YFDIKASSTY DRVLSGDGVP FAKWFDGATL NYAEHAFLHA RPEEVAIISK SEIRPLEKMT
WQTLQEKVAS FAAGLKAEGI KSGDRVVAYL PNIPEATIAF LACASIGAVW SSCSPDFGSR
TVIDRFQQIE PKLLIAVDGY RYNGKDHDRI DAVYEIQRSI PSLKKTILLP YLSENPNTDV
LTNIESWDEF IKEHQTTSLS YTQVPFDHPL WILYSSGTTG LPKAIVQGHG GILLEHLKKL
TFHTDLKPED NFFWYTTTGW MMWNIVVSGL LTGSTIVLYD GSPAYPNMET LWAFAEETEM
TVFGTSASYL VANKNNGEKP MDKYDLRHLK SVASTGSPLP PEGSEWVYEN IKKDLWLASV
SGGTDLCSAF VTGSPLLPVY AGEIQCRALG ANVQAYTEDA EPVFDEVGEL VLLEPMPSMP
LYFWNDTNNE RYYSSYFEEF PGIWRHGDWI KITSRGSCQI YGRSDSTINR GGIRMGTSEI
YSAVDDIDAV EDSLVIDIND PDGKDYMPLF VVLKEGEELN DELKKDINQG IRSQCSPRHV
PNDIFAIDEV PTTLNGKKME VPIKKLLTGT PVEKAVNTGS MKNPETLRYF QNFYHHHER
//
