ID   A0A1G8L4B2_9BRAD        Unreviewed;       860 AA.
AC   A0A1G8L4B2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Serralysin {ECO:0000313|EMBL:SDI50397.1};
GN   ORFNames=SAMN05216338_102415 {ECO:0000313|EMBL:SDI50397.1};
OS   Bradyrhizobium sp. Rc2d.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=1855321 {ECO:0000313|EMBL:SDI50397.1, ECO:0000313|Proteomes:UP000198770};
RN   [1] {ECO:0000313|EMBL:SDI50397.1, ECO:0000313|Proteomes:UP000198770}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rc2d {ECO:0000313|EMBL:SDI50397.1,
RC   ECO:0000313|Proteomes:UP000198770};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- SIMILARITY: Belongs to the peptidase M10B family.
CC       {ECO:0000256|ARBA:ARBA00009490}.
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DR   EMBL; FNCU01000024; SDI50397.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8L4B2; -.
DR   STRING; 1855321.SAMN05216338_102415; -.
DR   Proteomes; UP000198770; Unassembled WGS sequence.
DR   GO; GO:0031012; C:extracellular matrix; IEA:InterPro.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd04277; ZnMc_serralysin_like; 1.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 1.
DR   InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR   InterPro; IPR001343; Hemolysn_Ca-bd.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR001818; Pept_M10_metallopeptidase.
DR   InterPro; IPR013858; Peptidase_M10B_C.
DR   InterPro; IPR006026; Peptidase_Metallo.
DR   InterPro; IPR034033; Serralysin-like.
DR   InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR   InterPro; IPR011121; Trp-rich_dom.
DR   PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR   PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR   Pfam; PF00353; HemolysinCabind; 1.
DR   Pfam; PF00413; Peptidase_M10; 1.
DR   Pfam; PF08548; Peptidase_M10_C; 1.
DR   Pfam; PF07483; W_rich_C; 3.
DR   PRINTS; PR00313; CABNDNGRPT.
DR   SMART; SM00235; ZnMc; 1.
DR   SUPFAM; SSF51120; beta-Roll; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR   PROSITE; PS00330; HEMOLYSIN_CALCIUM; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          20..195
FT                   /note="Peptidase metallopeptidase"
FT                   /evidence="ECO:0000259|SMART:SM00235"
SQ   SEQUENCE   860 AA;  89379 MW;  1BC987E1643F44CC CRC64;
     MATAVTVTKT NNADIDGLLS GYKWSGAITY SFPDSSSDYA NPYTGGSSEP TTSGFASAPT
     QMQVAINYAI GLINGYTNAN IQYAGTNGAD IMIAQSPSAN PTSYAYYPGN YASGGDVWFG
     TQYNYSLAKL GNYYFVTALH ELGHAIGLKH SQETGGPANV AVPTAHDDSE YTVMSYRSYV
     GASTTSGYTN EAYGYPQTYM ANDILALQTM YGANFTTQSS NTVYTWNPTT GQEFINGVGQ
     PAPGGGVGGS ANRIYETVWD GGGVDTYDLS AYTTNLSINL NPGASSVFSS IQLAYLGDGH
     YASGNVYNAY LYNGDARSYI DNAIGGSGND TILGNAIANT LNGGSGNDTL TGGGGNDTII
     GGSGTDIALF SGNQSNYAVS YNSATQTFTL VDQRSGSPDG TDTVTGVESF QFADGTVTSA
     ALISLIGPIV IEAMGTTTLT QQGANYFLNP VGGGTGPQLK YGGSAVVAGQ FSPWTLIGAE
     QTATGYEIAF KQPGTDYFTI WNTDSFGNYL GNPTGIVLGT SSTLESLEAS FHQDLNGDGV
     LGIPTTVIEA FGSTSLVQIG SNYYLNPTAG GSGPELMYHG AAVVTGQFNP WSLIGAEQTS
     TGYEIAFKQP GTDYFTIWNT DSFGNYLGNP TGIVLGTSST LESLEASFHQ DLNGDGVLGI
     PTTVIEAFGS TSLVQIGSNY YLNPTAGGSG PELMYHGAAV VTGQFNPWNL IGAEQTSTGY
     EIAFKQPGTS YFTIWNTDSA GNYLGNPTGI VPGTSSALET FEPSFHQDLN GDGVIGVPAG
     TAPAVFASSH NFNFDSLAAA VGTAVGDGKG GANLIDIAQA WSGGARHDPV PFSITHAQVE
     HGDLPSIHVA DLHWTDFIIR
//