ID A0A1G8M847_9NOCA Unreviewed; 349 AA.
AC A0A1G8M847;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Predicted naringenin-chalcone synthase {ECO:0000313|EMBL:SDI64136.1};
GN ORFNames=SAMN05444695_109138 {ECO:0000313|EMBL:SDI64136.1};
OS Rhodococcus triatomae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=300028 {ECO:0000313|EMBL:SDI64136.1, ECO:0000313|Proteomes:UP000183263};
RN [1] {ECO:0000313|EMBL:SDI64136.1, ECO:0000313|Proteomes:UP000183263}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44892 {ECO:0000313|EMBL:SDI64136.1,
RC ECO:0000313|Proteomes:UP000183263};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; FNDN01000009; SDI64136.1; -; Genomic_DNA.
DR RefSeq; WP_072736836.1; NZ_FNDN01000009.1.
DR AlphaFoldDB; A0A1G8M847; -.
DR OrthoDB; 9786288at2; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000183263; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Reference proteome {ECO:0000313|Proteomes:UP000183263}.
FT DOMAIN 6..203
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 215..348
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 142
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 349 AA; 37665 MW; 0AAA23118CF417FC CRC64;
MTTAYINRIS TAVPEHDVHQ AFVDFADNTF TERRKQLLFR RMADRAQISH RWAGIGSPDS
FYGDDPNSVT TETRMIEFER NAPGLATRAV DGLNLGDQAA EVTHLIVISC TGFFSPGIDF
EIIEKCGVPM SVERTTIGFM GCFAGINGLK TAHHIVRSEP NAKVLVVSLE LCSLHLQRSD
SLETMLSFLV FGDGCAAVLV SAEEEGIAID SFKALMVPES AELITWRIGD IGFDMVLSGK
VPGVLSRTLD EPNVKSILSG AEKDSINLWA VHPGGRSILD AVEEAVGLEP EALSPSRHVL
DNYGNMSSAT VLFVLAEMME RAKNGGPTGS GCAMAFGPGL TAETMLFHI
//
