ID   A0A1G8NDB1_9MICC        Unreviewed;       379 AA.
AC   A0A1G8NDB1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Cation:H+ antiporter {ECO:0000313|EMBL:SDI78244.1};
GN   ORFNames=SAMN04488693_12313 {ECO:0000313|EMBL:SDI78244.1};
OS   Arthrobacter subterraneus.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Arthrobacter.
OX   NCBI_TaxID=335973 {ECO:0000313|EMBL:SDI78244.1, ECO:0000313|Proteomes:UP000199258};
RN   [1] {ECO:0000313|EMBL:SDI78244.1, ECO:0000313|Proteomes:UP000199258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NP_1H {ECO:0000313|EMBL:SDI78244.1,
RC   ECO:0000313|Proteomes:UP000199258};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FNDT01000023; SDI78244.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8NDB1; -.
DR   STRING; 335973.SAMN04488693_12313; -.
DR   Proteomes; UP000199258; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.20.1420.30; NCX, central ion-binding region; 1.
DR   Gene3D; 6.10.280.80; NCX, peripheral helical region; 1.
DR   InterPro; IPR004481; K/Na/Ca-exchanger.
DR   InterPro; IPR004837; NaCa_Exmemb.
DR   InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR   NCBIfam; TIGR00367; calcium/sodium antiporter; 1.
DR   PANTHER; PTHR10846:SF8; INNER MEMBRANE PROTEIN YRBG; 1.
DR   PANTHER; PTHR10846; SODIUM/POTASSIUM/CALCIUM EXCHANGER; 1.
DR   Pfam; PF01699; Na_Ca_ex; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199258};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        74..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        185..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        249..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        313..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        339..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..138
FT                   /note="Sodium/calcium exchanger membrane region"
FT                   /evidence="ECO:0000259|Pfam:PF01699"
FT   DOMAIN          184..326
FT                   /note="Sodium/calcium exchanger membrane region"
FT                   /evidence="ECO:0000259|Pfam:PF01699"
SQ   SEQUENCE   379 AA;  38367 MW;  8151630C2ECA4BE6 CRC64;
     MGRIVAGLVL LVLGGEFLVR GASALARRVG ISSLVVGLTV VSAATSAPEL AVTIGAVLRD
     EPGLAVGNVV GSNIVNVLLI LGLSALVVPL AVKQRLVRFD LPLMVALSVG VLLVSLDGRI
     SAVDGLVLFC VVVVHTVMTV VIGRRDAKIP TTPDPAGGSP TADSATADSA GEKEAAPADS
     FAKSLLLVLL GIALLVAGAT LLVEGAVSIA ATLGVSSLVV GLTVVAVGTS LPELATSIIA
     VRRGERDLAV GNVVGSNIFN IGVVLGLPAL ISLEGIPVSA AAVAFDIPVM LAAAVALLPV
     AFTGFAIARW EGILFVGLYL AYTGYVVLTA TAHDALEGFT AAMAWFVLPL IAATLISFTA
     YEIGLHKGRR NPDQTRTSP
//