ID   A0A1G8NIC4_9ACTN        Unreviewed;       695 AA.
AC   A0A1G8NIC4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Dipeptidyl-peptidase-4 {ECO:0000313|EMBL:SDI79250.1};
GN   ORFNames=SAMN05421869_107117 {ECO:0000313|EMBL:SDI79250.1};
OS   Nonomuraea jiangxiensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=633440 {ECO:0000313|EMBL:SDI79250.1, ECO:0000313|Proteomes:UP000199202};
RN   [1] {ECO:0000313|EMBL:SDI79250.1, ECO:0000313|Proteomes:UP000199202}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.6533 {ECO:0000313|EMBL:SDI79250.1,
RC   ECO:0000313|Proteomes:UP000199202};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNDJ01000007; SDI79250.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8NIC4; -.
DR   STRING; 633440.SAMN05421869_107117; -.
DR   OrthoDB; 9812921at2; -.
DR   Proteomes; UP000199202; Unassembled WGS sequence.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002469; Peptidase_S9B_N.
DR   PANTHER; PTHR11731:SF193; DIPEPTIDYL PEPTIDASE 9; 1.
DR   PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR   Pfam; PF00930; DPPIV_N; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199202}.
FT   DOMAIN          108..374
FT                   /note="Dipeptidylpeptidase IV N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00930"
FT   DOMAIN          489..688
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
FT   REGION          66..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..88
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   695 AA;  75297 MW;  BC9E1FA4BA76E52F CRC64;
     MSESFPRLSA RTRRFTLGVP RSFTISPDGG RVIFLRTMSG TDSVTCLWEL DTETHVERLV
     VDPRGLLADD GEDLPPEERA RRERSREAAG GVVAYATDSG VTRAAFALSG GLHVVDLASG
     QVRRLETPGA VIDPRLSPDG RHVAYVTEGT LRVQDLVTGG DRALATPESE TVTYGLAEFV
     AAEEMDRMRG YWWAPSSDAL LVERADEAPV RTWHIADPAN PARPATVQRY PAAGTPNAVT
     ELYVLGLDGS RVAVPYAEEY LTTAAWDSHA LSIVTLTRDQ RTMRLFTVDP ATGAATLVRE
     DTDPAWVDIV AGVPAHLDDG SLVWVANSEG GHRLFVGDRP VTPPTLQVRA VLDVDHDSVL
     FSASGDPTEI HLWTWDGHSL LPVSTRSGVF SGRMSGGVGV LTEQSLDAEG VSTTVVRRDG
     VAVPIPSVAE RPGLDLRVSL GRSGRRELAT AVVLPSWHEQ GSRRLPVLMD PYGGPHAQRV
     LNRRGAFLES QWFAEQGFAV ILADGRGTPG RGVDFERAVL NDLASPALDD QIDALQGVAE
     QYPDDLDLTR VAIRGWSFGG FLAALAVLRR PDVFHAAVAG APVTDWRLYD TCYTERYLGH
     PDEQPEVYEK SSLFADAAKL ERPLFLIHGL ADDNVVAAHT LRLSSALLAA GRQHTVLPLS
     GVTHMTPQEV VAENLLLLQV DFLKKSLGGP WPDHP
//