ID   A0A1G8NV84_9BURK        Unreviewed;       378 AA.
AC   A0A1G8NV84;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=4-hydroxybutyrate dehydrogenase {ECO:0000313|EMBL:SDI84114.1};
GN   ORFNames=SAMN05444748_107317 {ECO:0000313|EMBL:SDI84114.1};
OS   Variovorax sp. OV700.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=1882826 {ECO:0000313|EMBL:SDI84114.1, ECO:0000313|Proteomes:UP000199505};
RN   [1] {ECO:0000313|Proteomes:UP000199505}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OV700 {ECO:0000313|Proteomes:UP000199505};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC         Evidence={ECO:0000256|ARBA:ARBA00001962};
CC   -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00007358}.
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DR   EMBL; FNDR01000007; SDI84114.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8NV84; -.
DR   STRING; 1882826.SAMN05444748_107317; -.
DR   OrthoDB; 9815791at2; -.
DR   Proteomes; UP000199505; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd14861; Fe-ADH-like; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR018211; ADH_Fe_CS.
DR   InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR   PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR   PROSITE; PS00913; ADH_IRON_1; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          8..369
FT                   /note="Alcohol dehydrogenase iron-type/glycerol
FT                   dehydrogenase GldA"
FT                   /evidence="ECO:0000259|Pfam:PF00465"
SQ   SEQUENCE   378 AA;  39920 MW;  03ED9F41322322B1 CRC64;
     MALIQYLTQI QFEFGAIKLL SSECARIGIN RPLIVTDAGV RAAGVLQKAL DAIADLEVAV
     FDQTPSNPTE AAVRAAVELY RSARCDGLIA VGGGSAIDCA KGVAIAATHE GPLKTYATIE
     GGSPKITDRV VPLIAVPTTS GTGSEVARGA IVIVDDHRKL GFHSWFLMPK AAICDPELTL
     GLPPKLTAAT GMDAIAHCME TFMSAAFNPP ADGIGLDGLE RAWLHIERAT KDGSDREARL
     NLMSASMQGA MAFQKGLGCV HSLSHSLGGV DPRLHHGTLN ALFLPAVIHF NAGAESVQKE
     QRLQRMAQAM HLDSAGDLGD AIRDMNARLG LPKGLAEVGV TPGMFEQIID GAMADHCHKT
     NPQLASRDDY KAMLEASM
//