ID A0A1G8P7B1_9FIRM Unreviewed; 466 AA.
AC A0A1G8P7B1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Putative hemolysin {ECO:0000313|EMBL:SDI88379.1};
GN ORFNames=SAMN04487760_10185 {ECO:0000313|EMBL:SDI88379.1};
OS Lachnospiraceae bacterium G41.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1200749 {ECO:0000313|EMBL:SDI88379.1, ECO:0000313|Proteomes:UP000199016};
RN [1] {ECO:0000313|EMBL:SDI88379.1, ECO:0000313|Proteomes:UP000199016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G41 {ECO:0000313|EMBL:SDI88379.1,
RC ECO:0000313|Proteomes:UP000199016};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the UPF0053 family.
CC {ECO:0000256|ARBA:ARBA00006337}.
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DR EMBL; FNEU01000001; SDI88379.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8P7B1; -.
DR STRING; 1200749.SAMN04487760_10185; -.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000199016; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF17; UPF0053 INNER MEMBRANE PROTEIN YFJD; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199016};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 234..293
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 303..360
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 466 AA; 53865 MW; CD6E589CA822615B CRC64;
MLASNYLGYE FYYFEDAWPF YIILVLLFIV ETLLSVSLYV VEDFNEANLL SIKEKLSSSD
EKSLQKFLKN KNRYINRFHA ALITAHMFVI LLAANIIIDI TDRFTLIADW SVILYILFIV
LIQFVFLFFN FLFFFLLPRR VFRHSSEYVK ALFTLFSLKI SVIMAPISDF SDFLITGFFN
IIGKSKYNKE DEVTEDDILS MVQESNDQGM IEDDEVAMIN NIFELNDKEA KDIMTNRKNI
VGINGDTKLS DAIKIMLEGS NSRYPVYIDS LDHIIGIIHL KDALRYQENN KDRDGAIRRY
PKLLREARFV SETRKIDDLF KKMKDDKLQM VIVIDEYGQT SGLVAMEDIL EEIVGNILDE
YDKEETFVES KGEKSYEIDG LTPLEELSDI LGIDMESEDE DIETINGFLT NKLGYVPEND
DKSVIEYGGY SFKILEVENH IIKSVFVTKL TSEDANNSAD FVDKQA
//
