ID   A0A1G8RXP4_9EURY        Unreviewed;      1886 AA.
AC   A0A1G8RXP4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=CARDB protein {ECO:0000313|EMBL:SDJ21305.1};
GN   ORFNames=SAMN05216226_101160 {ECO:0000313|EMBL:SDJ21305.1};
OS   Halovenus aranensis.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Halovenus.
OX   NCBI_TaxID=890420 {ECO:0000313|EMBL:SDJ21305.1, ECO:0000313|Proteomes:UP000198856};
RN   [1] {ECO:0000313|EMBL:SDJ21305.1, ECO:0000313|Proteomes:UP000198856}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBRC-M10015 {ECO:0000313|EMBL:SDJ21305.1,
RC   ECO:0000313|Proteomes:UP000198856};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNFC01000001; SDJ21305.1; -; Genomic_DNA.
DR   STRING; 890420.SAMN05216226_101160; -.
DR   Proteomes; UP000198856; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR011635; CARDB.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF07705; CARDB; 1.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198856};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1044..1302
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   1886 AA;  201399 MW;  A9285D7339EAE076 CRC64;
     MMREGAPGGE RAVSEIYGTF LIIAVVFLMA LVLVGVGMFA FEDITEDADN EVVQQSILEF
     DERVSELTAQ DVEGSTSIEF PDGTASDINA QSGHGNVNIT IKTHEAYWDA TDSPGALLED
     ADNQTASYSV TLGSLVYENN DGKITAYQGG AVWEKQSGDV SLVSPPDLYA DNQTLELSFV
     DISSIDLVQD GNEISLRKQP GAGSAAENIT ELVEQQMRSQ YPDGRYVANA TVSLNITSAF
     AEGWAEYAES NLGADTDVHE ASEVDGDRPV AEIDLGTYGE QNTINQSREY AENVTYTGLG
     EFAQDLYDNG TDDAWTADIA NQSNAAFNVT APGWDTKKYT VGILYNNDTR GNGPEWWAYN
     GTDGRWWNVE DPHAAPLNTS MIPESVVDAS QTDPGEDKFG VAADTWGCVV ATGDAHDPDD
     FRAFVPNATE YTASSSNGCL ESPVGVNTSE NWKDYVGDFE TDFVIDDFRT KIYNGSGVLV
     HDSSGGPTLD PNTDALEPGY EVEMTLNWTN EGYRNATAGE SPVAFVYDEK NKSETSITLP
     SDPWIVWGER VGTDKGENDS RTFSFPVENA DSVYEFWVGA GTKHDGVEPS ATWEVQVDTP
     STFEPSDISV DDAGAVEGDE VEVSVDINNT GSTGDSQTVF LWGSTPTDEE KHLINSTELT
     LPPDPPNNTT TETFTWTTQE GRESDWENVT VKAPVSGTKA AANISVDPAS SDPAEFTIES
     VSFNGTALSD GDFAGTVEEG EDAVVILNVN NTGGKEGIQQ VTLDRDGIDD DDSARTNSTT
     LELAPGDSPK QVALEWKTIP GDASGDPYTL KLQTDDDEFT FELTVLQRTD GSEFDVNIAS
     VSDPVLAGDT MFVNGTVTNT GEDDTQTLYL KTVGIPDQQS VAVDTGETKP FNMSWETGSG
     DVGTHNVTVL ADDDRDTAEN VSVEPRDLGE AEFDVSIEST TTPVTEGEPL AVDINVTNTG
     TAPGATVVAL KDFDDKFVNV TSEELSFAEG ESKQVTLTWY TLVGLVEGDA SVTDEITVDA
     DGQNATDTAS VTVKPRNATR LPADVVFAID ETGSMGDPDY FPEKVDTDPP KSGTLTVPED
     EMWLVTADES SCPGFFCDVF NDGYFVTGQT INFSAYNYDD WTNWEIEKYD YPSTGSDKNI
     ERVPAVWTAL SAMNKTLDRA AAMQYDTSQN FLTGLGDIAE VNESLRVAPG GNTDIAGAIS
     AAENKLVSET DLDYGNPDSD RYQTVILLTD GIDNSGADPV SVANETNMSH GSQPLDFSVY
     TVGFGNADEE VLKDVARYAG NGDGNYTKAD NPEELAGIFE GLIKEITEEK EPEVAINSAE
     INGSEDIAEG ETVTIEAEIE NAGEGVGDVP VTLLDWEGNP VDSTLVNVSS AGLASGESKT
     VQLSWDTTGV LDGDINTDNV TVVASGNENP TAVTVEDKSA FFDVGIQSVD DGVEEGETVT
     VNVSVENTDN APDTQTLWLE YQDESGNNQT LATSAPVELD GGENTSTSID WQTGIGDGDI
     ESITVHSEND MEAIPVDVKR KEVTEAEFAV DITTTASPVT IGDQLDVTAE IENVNGTDET
     YPGQVVLTVG SVEKDSKIVA LSDGESTTET FTWWTDDTGD SIDVEVRAAT DGGENSSSEE
     VTVDDVDNKE ETFKISDVAT NADDGVDSIT EDETLTVDID VKNDGDGAGS QTLIVRRNDS
     GQGERTDVTT VDTGTIPEDS TETVTVSLSP SDFSAETDKI IVESEDDFSG MQTVDIEPTD
     DTQVNIDIDE DAIAATDQAQ AVEAGEPISV PVEITNGGST DITEDLFVSL DAVLSPKSIE
     QSPANFTVLN IGTLAPENTT TATLVWDTTG AGWDDDHWQL TVESEGESDI VQVYVDELDG
     ALPGGPDFGG IGSGIDFTID DIEVAE
//