ID   A0A1G8S1I8_9ACTN        Unreviewed;       310 AA.
AC   A0A1G8S1I8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Nucleoside-diphosphate-sugar epimerase {ECO:0000313|EMBL:SDJ23097.1};
GN   ORFNames=SAMN05421874_101139 {ECO:0000313|EMBL:SDJ23097.1};
OS   Nonomuraea maritima.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=683260 {ECO:0000313|EMBL:SDJ23097.1, ECO:0000313|Proteomes:UP000198683};
RN   [1] {ECO:0000313|EMBL:SDJ23097.1, ECO:0000313|Proteomes:UP000198683}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.5681 {ECO:0000313|EMBL:SDJ23097.1,
RC   ECO:0000313|Proteomes:UP000198683};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNFB01000001; SDJ23097.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8S1I8; -.
DR   STRING; 683260.SAMN05421874_101139; -.
DR   OrthoDB; 9795501at2; -.
DR   Proteomes; UP000198683; Unassembled WGS sequence.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR   PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198683}.
FT   DOMAIN          6..249
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   310 AA;  33248 MW;  480D3870E96D1F8B CRC64;
     MAQAFVTGGS GFIGQVLVRR LLDEGHSVRV LVRSEASAAR VAALGAVPVR GELTDPATWR
     DRVTGSDVVF HLAAETDVAA DRERHELVSV RGTQAAVDAS RFARVPWFVH CGSEAALLAG
     DPLVDIDETA PLRPDSEAAY CAVKAVAEKI VLDANAPDFA TVSIRPRFVW GPGSILIEGL
     VAAAKAGQFA WIDGGRHTTD VTFVDNAVEG LMLGWQRGRP GQAYFITDRR RVTLREFMET
     LFAIYGVDAP IPDLDAETAD REVPVPVRWF LGQPCILRTD KAAAELGYEP IVPHAAGLDA
     VRDSVALSGV
//