ID   A0A1G8T108_9FIRM        Unreviewed;       921 AA.
AC   A0A1G8T108;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Membrane protein insertase, YidC/Oxa1 family, C-terminal domain-containing protein {ECO:0000313|EMBL:SDJ35198.1};
GN   ORFNames=SAMN04487760_105156 {ECO:0000313|EMBL:SDJ35198.1};
OS   Lachnospiraceae bacterium G41.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1200749 {ECO:0000313|EMBL:SDJ35198.1, ECO:0000313|Proteomes:UP000199016};
RN   [1] {ECO:0000313|EMBL:SDJ35198.1, ECO:0000313|Proteomes:UP000199016}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G41 {ECO:0000313|EMBL:SDJ35198.1,
RC   ECO:0000313|Proteomes:UP000199016};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC       {ECO:0000256|RuleBase:RU003945}.
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DR   EMBL; FNEU01000005; SDJ35198.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8T108; -.
DR   STRING; 1200749.SAMN04487760_105156; -.
DR   OrthoDB; 1835470at2; -.
DR   Proteomes; UP000199016; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd20070; 5TM_YidC_Alb3; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR   InterPro; IPR028055; YidC/Oxa/ALB_C.
DR   InterPro; IPR047196; YidC_ALB_C.
DR   PANTHER; PTHR12428:SF65; INNER MEMBRANE PROTEIN ALBINO3, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR12428; OXA1; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199016};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003945};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   TRANSMEM        145..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        255..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        365..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        436..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          34..222
FT                   /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02096"
SQ   SEQUENCE   921 AA;  104335 MW;  66BB3FF4C576940A CRC64;
     MSVFQVIYSV LIRPLQIFFE YVFSVAQKGL NNPGLSIIAL SLSMNLLVLP LYNRADAVQE
     EERNIENKLR KGVAHIRKTF KGDERMMMLQ TYYRQNGYKP TDVFKSSVSL LLEIPFFIAA
     YQFLSHLDAI QNVSFGPIAN LGAPDALITI GAFSINLLPI VMTSLNLISC IVFTKGYPLK
     NKIQLYAMAV FFFFFLYKSP AGLVFYWTLN NLFSLVKTIY YKSKTAKKVL NIAFSVVGVC
     LLGSLPFAMK KTGSKSFLLI LILLAFICFV PLAISIVSKK ELFKKKEIKE TDGKLFLLGG
     IYMTILTGIL IPSAVIKSSP QEFVDIYHFL NPLWFVLSAT CIAAGVFLVW FSVFYGLLDK
     KIKSILNVVM CVVCFVATVN YMFFGKNNVI LNSALAYTEE YTAPHKLILI NLLVIVAVIA
     ASVAITLLLG KKLRVFIIAG TLAILGMSVI NCTAIQKEIK GLKSVIESVN TEKPSFNLSK
     NGKNVIVFML DRGMNEYIPY FVNEKPELKE IYDGFCYYPN TISYGLCTNY GAPAIFGGYE
     YTPEEMNARD TELLRDKHDE ALKVMPALFY DEGYNVTVCD PPYAGYSTVP DLSIYNDYPN
     IRTFITKGYY WNAQKVNVSD RNFRNFFCYS ITKIAPLAIQ DHLYNHGSYN ESIGNKRFLD
     EMKNSTAIVK EGLYRCTGIN EEVMEDYLTI ANLVDMTEIS DDASDNFLMI DNELTHWPIY
     FKEPEYEVAY FVDNEAYEKE HADRYTVDGV TLEMNNDVQI GSYQVNMCAI LKIGAWLEYL
     KEQGVYDNTR IIIVSDHGKW VYHNEMFDLD GSGDDETDIE SYYPLLMIKD FDSHGFTVDE
     RFMTNADVPV YALDGIIENP VNPFTGNAIT NDAKEGPQKI LGSHNPDVIT NNGTVFVDGI
     WYSVEGDMRD KNNWKLLEDN R
//