ID A0A1G8TP01_9GAMM Unreviewed; 497 AA.
AC A0A1G8TP01;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=diacylglycerol O-acyltransferase {ECO:0000256|ARBA:ARBA00013244};
DE EC=2.3.1.20 {ECO:0000256|ARBA:ARBA00013244};
GN ORFNames=SAMN04488540_10839 {ECO:0000313|EMBL:SDJ43134.1};
OS Ferrimonas sediminum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Ferrimonadaceae; Ferrimonas.
OX NCBI_TaxID=718193 {ECO:0000313|EMBL:SDJ43134.1, ECO:0000313|Proteomes:UP000199527};
RN [1] {ECO:0000313|EMBL:SDJ43134.1, ECO:0000313|Proteomes:UP000199527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23317 {ECO:0000313|EMBL:SDJ43134.1,
RC ECO:0000313|Proteomes:UP000199527};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol
CC + CoA; Xref=Rhea:RHEA:10868, ChEBI:CHEBI:17815, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:58342, ChEBI:CHEBI:64615; EC=2.3.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00001039};
CC -!- PATHWAY: Glycerolipid metabolism; triacylglycerol biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004771}.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the long-chain O-acyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009587}.
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DR EMBL; FNEM01000008; SDJ43134.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8TP01; -.
DR OrthoDB; 9810950at2; -.
DR UniPathway; UPA00282; -.
DR Proteomes; UP000199527; Unassembled WGS sequence.
DR GO; GO:0004144; F:diacylglycerol O-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0019432; P:triglyceride biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR InterPro; IPR014292; Acyl_transf_WS/DGAT.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR045034; O-acyltransferase_WSD1-like.
DR InterPro; IPR009721; O-acyltransferase_WSD1_C.
DR InterPro; IPR004255; O-acyltransferase_WSD1_N.
DR NCBIfam; TIGR02946; acyl_WS_DGAT; 1.
DR PANTHER; PTHR31650:SF1; DIACYGLYCEROL O-ACYLTRANSFERASE TGS4-RELATED; 1.
DR PANTHER; PTHR31650; O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN; 1.
DR Pfam; PF06974; WS_DGAT_C; 1.
DR Pfam; PF03007; WS_DGAT_cat; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:SDJ43134.1};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SDJ43134.1}.
FT DOMAIN 4..266
FT /note="O-acyltransferase WSD1-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03007"
FT DOMAIN 315..452
FT /note="O-acyltransferase WSD1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06974"
SQ SEQUENCE 497 AA; 55441 MW; 3A1D83638972E4F7 CRC64;
MQTMNFMDSM FFFIESAQTP MHVTPLLVLK PDPEHREGFG VSLYRKLQSK TTVVAPFNWR
PRFSLTGKHR WQEVAVDLGY HLRFAAVPAP GRQAQLNELI CRIQSQPLDR TRPLWELYVI
DGMSDGTVVL YMKLHHALFD GTRINGYARK MLTQSPVHND WVPIWQHEVY APQPEAPSSG
RLRTSLEALG NTLTQARMLP QAMRLGARVF GGALGMLPKR SKTPLTAPRS VLNTTPARGR
SFASQQWSLE RVRAIGKLTG ASFNDIILTC GDMALQRYLS RNHRLPDKPL VVLMPMNVRQ
PGDMTSNNQF VPGLVELQPP ELLPLPRLKR IQAAATDTKN EIREFSPALY EKYGVLMQAV
SMIAGKYGLE SKLPASSNLV ISTVPGLAEV RYLMGAEVVQ VAPMSALPPG QCLNISAYTY
NGKVCLGFLG CRKVLPDIGL LANDMDRALD ELELAALTQP KTSLFDRYLP HLANKRVSLH
SNPEGVILKQ RQSTGVR
//
