ID   A0A1G8TQ58_9RHOB        Unreviewed;       325 AA.
AC   A0A1G8TQ58;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000313|EMBL:SDJ43716.1};
GN   ORFNames=SAMN04488026_101767 {ECO:0000313|EMBL:SDJ43716.1};
OS   Aliiruegeria lutimaris.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Aliiruegeria.
OX   NCBI_TaxID=571298 {ECO:0000313|EMBL:SDJ43716.1, ECO:0000313|Proteomes:UP000199382};
RN   [1] {ECO:0000313|EMBL:SDJ43716.1, ECO:0000313|Proteomes:UP000199382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 25294 {ECO:0000313|EMBL:SDJ43716.1,
RC   ECO:0000313|Proteomes:UP000199382};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the vitamin-B12 dependent methionine synthase
CC       family. {ECO:0000256|ARBA:ARBA00010398}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNEK01000017; SDJ43716.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8TQ58; -.
DR   STRING; 571298.SAMN04488026_101767; -.
DR   OrthoDB; 9803687at2; -.
DR   Proteomes; UP000199382; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR   InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR   InterPro; IPR000489; Pterin-binding_dom.
DR   PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR   PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR   Pfam; PF00809; Pterin_bind; 1.
DR   SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
PE   3: Inferred from homology;
KW   Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:SDJ43716.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199382};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SDJ43716.1}.
FT   DOMAIN          21..280
FT                   /note="Pterin-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50972"
SQ   SEQUENCE   325 AA;  34601 MW;  CFE90E89D8FFA303 CRC64;
     MTRTVIESKT KTVTIGFDEP FCVIGERINP TGRKKLAAEL EAGDFSTVEK DALEQVACGA
     MVLDVNSGAV FTNKMAEDPR YADNNFVEPM LMKELITRIQ AIVDVPLCID SSVPGALQNG
     LEMAEGRPLL NSVTGEEERL EAILPLVKKY NVPVVAISND DTGISEDPDV RFAVAKKIVE
     RAADFGIPAH DIVVDPLVMP VGAMATAGQQ VFTLVRRLRD ELGVNTTCGA SNISFGLPNR
     HGVNAAFLPM AIGAGMTSAI MNPVRSVEME AIRAANLLMN HDPNGGAWIG LAKVLDAVKE
     GASFTEASQA AAAAGSGRGR RRRRG
//