ID A0A1G8U9E8_9ACTN Unreviewed; 572 AA.
AC A0A1G8U9E8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Choline/carnitine/betaine transport {ECO:0000313|EMBL:SDJ49620.1};
GN ORFNames=SAMN05421806_101681 {ECO:0000313|EMBL:SDJ49620.1};
OS Streptomyces indicus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=417292 {ECO:0000313|EMBL:SDJ49620.1, ECO:0000313|Proteomes:UP000199155};
RN [1] {ECO:0000313|EMBL:SDJ49620.1, ECO:0000313|Proteomes:UP000199155}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.5727 {ECO:0000313|EMBL:SDJ49620.1,
RC ECO:0000313|Proteomes:UP000199155};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family.
CC {ECO:0000256|ARBA:ARBA00005658}.
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DR EMBL; FNFF01000001; SDJ49620.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8U9E8; -.
DR STRING; 417292.SAMN05421806_101681; -.
DR OrthoDB; 9775735at2; -.
DR Proteomes; UP000199155; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR InterPro; IPR018093; BCCT_CS.
DR InterPro; IPR000060; BCCT_transptr.
DR NCBIfam; TIGR00842; bcct; 1.
DR PANTHER; PTHR30047:SF7; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30047; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF02028; BCCT; 1.
DR PROSITE; PS01303; BCCT; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199155};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 572 AA; 61247 MW; FB490C1089C8C4D1 CRC64;
MPHDEHNSPQ KHEKRAGRGD PHLSAGLPGS PHDHGAVTTD RVVFGVTAAL TLAFVLWGAI
ATDTLEDVSQ KALNGLIHNA GWAFVLAASG FVVFALWLAI SRYGKITLGG EGEDPEFRTV
SWVAMMFSAG MGIGLMFYGV SEPLAHFTTP PPGTDPADSA TAMMTAMATT LFHWTLHPWA
IYAVVGLAIA YSSFRKRRRQ TISAVFTPLI GKKHADGGWG RVIDILAIFA TLFGSAASLG
LGTLQISSGM RELDWAKTIS TGVLVAIIAV LTAAFVLSAV SGVDKGIQWL SNTNMVLALI
LALFVFIAGP TVIVLDLLPT SIASYFGDLP QLAGRTEASG GEGVADWLGS WTVFYWAWWI
SWTPFVGMFI ARISRGRTIR QFVGGVILVP STVSLVWFAI FGGTAMKMKE SGRLADESTP
EGQLFALLRE FPIPTVMSIL VMILVGIFFV SGADAASIVM GTLSQRGTFE PTRFVVVFWG
VVTGAVAAVM LMIGNGKPNA LQGLQNLTIL AAAPFVVVML GMCWALMRDL RKDPLIVRGE
KGEEAVEMAV IAGHEKYDGE FELRIGPAPT ED
//
