ID   A0A1G8UZS4_9ACTN        Unreviewed;       402 AA.
AC   A0A1G8UZS4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=alanine transaminase {ECO:0000256|ARBA:ARBA00026106};
DE            EC=2.6.1.2 {ECO:0000256|ARBA:ARBA00026106};
GN   ORFNames=SAMN05421806_1011165 {ECO:0000313|EMBL:SDJ59318.1};
OS   Streptomyces indicus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=417292 {ECO:0000313|EMBL:SDJ59318.1, ECO:0000313|Proteomes:UP000199155};
RN   [1] {ECO:0000313|EMBL:SDJ59318.1, ECO:0000313|Proteomes:UP000199155}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.5727 {ECO:0000313|EMBL:SDJ59318.1,
RC   ECO:0000313|Proteomes:UP000199155};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00007441}.
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DR   EMBL; FNFF01000001; SDJ59318.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8UZS4; -.
DR   STRING; 417292.SAMN05421806_1011165; -.
DR   OrthoDB; 9763453at2; -.
DR   Proteomes; UP000199155; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR43488; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR   PANTHER; PTHR43488:SF2; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199155}.
FT   DOMAIN          34..393
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
SQ   SEQUENCE   402 AA;  44516 MW;  C575F10737B1365A CRC64;
     MEFRQSSKLS EVCYEIRGPV IEQANALEEA GHSVLRLNTG NPALFGFEAP EEIVQDMIRM
     LPQAHGYTDS RGILSARRAV AQRYQTLGLD VDVDDVYLGN GVSELVSMAV QALVEDGDEI
     LIPAPDFPLW TAVTTLSGGK AVHYLCDEQA DWNPDLADIE SKITDRTKAL VIINPNNPTG
     AVYPKEIVEG MLDLARRHSL MVLADEIYDQ ILYDDAVHHS AAALAPDLVV LTFCGLSKTY
     RVAGFRSGWL VVTGPKQHAK DYLEGLTMLA SMRLCPNAPA QYAIQAALGG RQSIHELTAP
     GGRLREQRDV AWERLNEIPG VSCVKPKGSL YAFPRLDPKV HKIVDDEKFV LDLLLREKIQ
     VVQGTGFNWP RPDHFRILTL PYADDLDAAI SRIGRFLSGY RQ
//