ID A0A1G8V0H3_9PSED Unreviewed; 401 AA.
AC A0A1G8V0H3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=cysteine desulfurase {ECO:0000256|ARBA:ARBA00012239};
DE EC=2.8.1.7 {ECO:0000256|ARBA:ARBA00012239};
GN ORFNames=SAMN05216186_10257 {ECO:0000313|EMBL:SDJ59571.1};
OS Pseudomonas indica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=137658 {ECO:0000313|EMBL:SDJ59571.1, ECO:0000313|Proteomes:UP000198706};
RN [1] {ECO:0000313|EMBL:SDJ59571.1, ECO:0000313|Proteomes:UP000198706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 21544 {ECO:0000313|EMBL:SDJ59571.1,
RC ECO:0000313|Proteomes:UP000198706};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-
CC alanine; Xref=Rhea:RHEA:43892, Rhea:RHEA-COMP:14737, Rhea:RHEA-
CC COMP:14739, ChEBI:CHEBI:29917, ChEBI:CHEBI:35235, ChEBI:CHEBI:57972,
CC ChEBI:CHEBI:64428; EC=2.8.1.7;
CC Evidence={ECO:0000256|ARBA:ARBA00001357};
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU004504};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. Csd subfamily.
CC {ECO:0000256|ARBA:ARBA00010447}.
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DR EMBL; FNFD01000002; SDJ59571.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8V0H3; -.
DR STRING; 137658.SAMN05216186_10257; -.
DR Proteomes; UP000198706; Unassembled WGS sequence.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0006534; P:cysteine metabolic process; IEA:InterPro.
DR CDD; cd06453; SufS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR InterPro; IPR010970; Cys_dSase_SufS.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR43586; CYSTEINE DESULFURASE; 1.
DR PANTHER; PTHR43586:SF27; CYSTEINE DESULFURASE 1, CHLOROPLASTIC; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000198706}.
FT DOMAIN 23..389
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 401 AA; 43026 MW; BB97DB770EE0871E CRC64;
MALDSPWRSD FPALAAFEAE GQVYLDSAAT AQKPQAVLDA LLGYYTSGAA NVHRAQHLPG
ERATRAFEAT RTKATHWLNA HSPAEIVFTR GATEAFNLLA YGLEAEFEAG DEIVISALEH
HANLLPWQQL ALRRGLRLLV LPLTAEGVVD MDAARELIGP QTRLLAISQL SNVLGCWQPL
TELIALAKVH DALTVVDGAQ GVVHGRHDVQ VLGCDFYVFS SHKLYGPEGV GVLYGRSEAL
QRLRHWQFGG EMVHLADYHS ADFHGAPMGF EAGTPPIGGV IALGAALDYL GSLDTGALFA
HEAVLHGKLL AGLKVRDGVR VLGTPQAALA SFVVDGVHTA DLAHLLGEQG IAVRAGQHCA
MPLYKRLGLT GAIRVSLGLY NDTADLDHFF TALDRALELL R
//
