ID   A0A1G8W1U3_9ACTN        Unreviewed;       452 AA.
AC   A0A1G8W1U3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=Ammonium transporter {ECO:0000256|RuleBase:RU362002};
GN   ORFNames=SAMN05421806_102141 {ECO:0000313|EMBL:SDJ71420.1};
OS   Streptomyces indicus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=417292 {ECO:0000313|EMBL:SDJ71420.1, ECO:0000313|Proteomes:UP000199155};
RN   [1] {ECO:0000313|EMBL:SDJ71420.1, ECO:0000313|Proteomes:UP000199155}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.5727 {ECO:0000313|EMBL:SDJ71420.1,
RC   ECO:0000313|Proteomes:UP000199155};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362002};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU362002}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC       family. {ECO:0000256|ARBA:ARBA00005887, ECO:0000256|RuleBase:RU362002}.
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DR   EMBL; FNFF01000002; SDJ71420.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8W1U3; -.
DR   STRING; 417292.SAMN05421806_102141; -.
DR   OrthoDB; 9814202at2; -.
DR   Proteomes; UP000199155; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR   InterPro; IPR029020; Ammonium/urea_transptr.
DR   InterPro; IPR001905; Ammonium_transpt.
DR   InterPro; IPR018047; Ammonium_transpt_CS.
DR   InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR   NCBIfam; TIGR00836; amt; 1.
DR   PANTHER; PTHR43029; AMMONIUM TRANSPORTER MEP2; 1.
DR   PANTHER; PTHR43029:SF10; AMMONIUM TRANSPORTER MEP2; 1.
DR   Pfam; PF00909; Ammonium_transp; 1.
DR   SUPFAM; SSF111352; Ammonium transporter; 1.
DR   PROSITE; PS01219; AMMONIUM_TRANSP; 1.
PE   3: Inferred from homology;
KW   Ammonia transport {ECO:0000256|ARBA:ARBA00023177,
KW   ECO:0000256|RuleBase:RU362002};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199155};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362002};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362002};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362002}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        52..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        139..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        180..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        211..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        240..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        269..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        296..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        327..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        366..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   DOMAIN          21..418
FT                   /note="Ammonium transporter AmtB-like"
FT                   /evidence="ECO:0000259|Pfam:PF00909"
FT   REGION          419..452
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   452 AA;  46474 MW;  89647957B55E6882 CRC64;
     MPPGILLAAE EPTLSSANTG FMLICSALVM LMTPGLAFFY GGMVRVKSTL NMLMMSFISL
     GIVTILWVLY GFSVAFGTDK GGLIGWEGDF LGLSGLGLTE LWPGYTIPVY VFAVFQLMFA
     VLTPALISGA LADRVKFTAW ALFVALWATL VYFPVAHWVW GAGGWAFELG VIDFAGGTAV
     HINAGAAALG VILVIGKRVG FKKDPMRPHS LPLVMLGAGL LWFGWFGFNA GSWLGNDDGV
     GAVMFVNTQV ATAAAMLAWL AYEKIRHGAF TTLGAASGAV AGLVAITPSG GSCSPLGAIA
     IGAIAGVLCA MAVGLKYKFG YDDSLDVVGV HLVGGVVGSL LVGFFATGGV QNDAKGLFYG
     GDASQLGYQA AGVFGTLAYS LVVSAILAFV IDKTIGMRVS EDDEVAGVDT VEHAESAYDF
     SGAGGGTAPR TAAVPAPPAT PAPEAPAKKV DA
//