ID   A0A1G8W3F0_9EURY        Unreviewed;       534 AA.
AC   A0A1G8W3F0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=SAMN05216226_10842 {ECO:0000313|EMBL:SDJ72603.1};
OS   Halovenus aranensis.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Halovenus.
OX   NCBI_TaxID=890420 {ECO:0000313|EMBL:SDJ72603.1, ECO:0000313|Proteomes:UP000198856};
RN   [1] {ECO:0000313|EMBL:SDJ72603.1, ECO:0000313|Proteomes:UP000198856}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBRC-M10015 {ECO:0000313|EMBL:SDJ72603.1,
RC   ECO:0000313|Proteomes:UP000198856};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FNFC01000008; SDJ72603.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8W3F0; -.
DR   STRING; 890420.SAMN05216226_10842; -.
DR   OrthoDB; 327291at2157; -.
DR   Proteomes; UP000198856; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd00075; HATPase; 1.
DR   CDD; cd12914; PDC1_DGC_like; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   PANTHER; PTHR44936:SF9; SENSOR HISTIDINE KINASE GLNK; 1.
DR   PANTHER; PTHR44936; SENSOR PROTEIN CREC; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SDJ72603.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198856};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        240..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          264..316
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          324..527
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   534 AA;  58075 MW;  8A2E84BA582F0AD5 CRC64;
     MKLAHRYTIL FLVVVLVSGG VLLTTFTAHR SDVTENAETD VTDRAEQMAT FLDNELREQR
     RVVEFAATDE NAVDHGSEAQ RAILESFVET TSFNGVSVVD ETGTIRALVT DDGPQTDLVG
     SDISDRTYVR RALAGEHYVS EPFTADTGNR IAVMSVPLAV DGETAGSINA AYHLDSTKMF
     SVLASKDVDA SVTVESNDLM LYSTAGDKET ITRQAALDVA DWTVKAHYSK DAIDASTRQL
     AVFQGVVGLV LLGTLAIFGG WVYRAQILQI NQVLGQLNAL EQRQYDQRVD LGGGHEWEQI
     EQALAELREA LTQREQMLLV HNRILRHNLR NKLNVIRSQT ELLDAGDETV STETTKIRRA
     TDTLLQLADR ARTTDQLLDP PEQDARVDLS RVVHDRATAI AESYPALSVT ISAPESAYAA
     CGAEIGTAID ELLQNVVDHA GPEPTATVTV VEAGEYVVVR VEDDGDGIPE SEAEVITGDH
     DITQLHHTVG IGLRLVDWIA SRYDGTLNVP QTGGTGCAIE IELPRAHPPD ETAA
//