ID   A0A1G8WFG6_9FIRM        Unreviewed;       475 AA.
AC   A0A1G8WFG6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Isopropylmalate/homocitrate/citramalate synthases {ECO:0000313|EMBL:SDJ76827.1};
GN   ORFNames=SAMN04487760_11435 {ECO:0000313|EMBL:SDJ76827.1};
OS   Lachnospiraceae bacterium G41.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1200749 {ECO:0000313|EMBL:SDJ76827.1, ECO:0000313|Proteomes:UP000199016};
RN   [1] {ECO:0000313|EMBL:SDJ76827.1, ECO:0000313|Proteomes:UP000199016}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G41 {ECO:0000313|EMBL:SDJ76827.1,
RC   ECO:0000313|Proteomes:UP000199016};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNEU01000014; SDJ76827.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8WFG6; -.
DR   STRING; 1200749.SAMN04487760_11435; -.
DR   OrthoDB; 9804858at2; -.
DR   Proteomes; UP000199016; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   CDD; cd07947; DRE_TIM_Re_CS; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR000891; PYR_CT.
DR   PANTHER; PTHR42880; HOMOCITRATE SYNTHASE; 1.
DR   PANTHER; PTHR42880:SF1; ISOPROPYLMALATE_HOMOCITRATE_CITRAMALATE SYNTHASE FAMILY PROTEIN; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199016};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          71..341
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
SQ   SEQUENCE   475 AA;  54600 MW;  D8A2929913BF4D1C CRC64;
     MSNLSSDVYE NFQNRPVSLN PRNNLLEIEE HMYILEDVDK PNVFRNMFPY SEVPKIPFND
     RIVPHNMPKD IWITDTTFRD GQQSRAPYST EQIVTIYDYL HRLGGPNGMI RASEFFLYSK
     KDRDAVVKCM ERGYKFPEVT SWIRASEKDF QLVKEIGMKE TGILVSCSDY HIFLKLKMTR
     RQALDHYLSI IRQCLDCGIS PRCHLEDITR SDIYGFVVPF AMELMKLMDE YKIPIKIRLC
     DTMGYGVNFP GAVIPRSVQG TIYALHVNAG VPHELLEWHG HNDFYKAVVN STTAWLYGCS
     GVNTSLFGIG ERTGNTPLEA MVFEYAQLKG DLNGMDTTVI TELAEYYEKE IGYHIPPMTP
     FVGKNFNVTR AGIHADGLLK NEEIYSIFDT DKFLNRPVMC AISNTSGLAG IAHWMNHHYH
     LKGDSELDKK DDIVVKLKEW VDKQYEEGRV TVLTDNELEN QINVICEEYG MPLFI
//