ID   A0A1G8WJS6_9FIRM        Unreviewed;       501 AA.
AC   A0A1G8WJS6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Sortase, SrtB family {ECO:0000313|EMBL:SDJ78441.1};
GN   ORFNames=SAMN04487760_11520 {ECO:0000313|EMBL:SDJ78441.1};
OS   Lachnospiraceae bacterium G41.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1200749 {ECO:0000313|EMBL:SDJ78441.1, ECO:0000313|Proteomes:UP000199016};
RN   [1] {ECO:0000313|EMBL:SDJ78441.1, ECO:0000313|Proteomes:UP000199016}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G41 {ECO:0000313|EMBL:SDJ78441.1,
RC   ECO:0000313|Proteomes:UP000199016};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNEU01000015; SDJ78441.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8WJS6; -.
DR   STRING; 1200749.SAMN04487760_11520; -.
DR   Proteomes; UP000199016; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd05826; Sortase_B; 1.
DR   Gene3D; 2.40.260.10; Sortase; 1.
DR   InterPro; IPR005754; Sortase.
DR   InterPro; IPR023365; Sortase_dom-sf.
DR   InterPro; IPR009835; SrtB.
DR   Pfam; PF04203; Sortase; 1.
DR   SUPFAM; SSF63817; Sortase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199016};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        429..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        462..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          253..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        303..320
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        136
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT   ACT_SITE        228
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ   SEQUENCE   501 AA;  56860 MW;  DEA9BA2DD170EBFB CRC64;
     MQSTNINKLI DKISIWGIRV LVTASLLLGF GLMLFSGYAI YEQYYTQSRA FSSGGINTAE
     VYTVEAQQNL VQSRKDYRAW LKIDNTNIDY PVMQSSDDIY YANHDIDGNM SLTGAIYMAA
     DNTADLSDDY IVIYGHHMDV GAMFGDLDKF LDKDFFDSNN SGKFVFPDGS VFDLKLWAVV
     HTDAYEDEVY SVGTQKFDEV VEYVNKYSKY IKPSSLENAK KIVALSTCYD AMTNGRIVVF
     YTLKEEQKAV VPKNPTTPIN DEDTGITTPV DKPTGMGITT PDYVVPTTPD NPAKPDNPDK
     PTTPDDNPTT TPEEVDTTPT SWWVPSGSSY GTKAWAIINL ICLIITVYIL VPIFFLRKKY
     GRIHKMRKVN KTKEELFDAQ DMTPEDWTER ERIMTAATKK SENGYVSKDK FSEAVEELFF
     KVKVFTRKFI VGIVLEVIFV IAGVIIFILT EDMTLPMVLI DRWTPVMLLL MIGSMLADYI
     LARYKRPKKE KNDENEIRLN D
//