ID   A0A1G8XQQ1_9ACTN        Unreviewed;       746 AA.
AC   A0A1G8XQQ1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=ATP-dependent exoDNAse (Exonuclease V), alpha subunit, helicase superfamily I {ECO:0000313|EMBL:SDJ92868.1};
GN   ORFNames=SAMN05421806_103350 {ECO:0000313|EMBL:SDJ92868.1};
OS   Streptomyces indicus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=417292 {ECO:0000313|EMBL:SDJ92868.1, ECO:0000313|Proteomes:UP000199155};
RN   [1] {ECO:0000313|EMBL:SDJ92868.1, ECO:0000313|Proteomes:UP000199155}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.5727 {ECO:0000313|EMBL:SDJ92868.1,
RC   ECO:0000313|Proteomes:UP000199155};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNFF01000003; SDJ92868.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G8XQQ1; -.
DR   STRING; 417292.SAMN05421806_103350; -.
DR   Proteomes; UP000199155; Unassembled WGS sequence.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.30.940; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR029493; RecD-like_HHH.
DR   Pfam; PF13604; AAA_30; 1.
DR   Pfam; PF14490; HHH_4; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:SDJ92868.1};
KW   Exonuclease {ECO:0000313|EMBL:SDJ92868.1};
KW   Helicase {ECO:0000313|EMBL:SDJ92868.1};
KW   Hydrolase {ECO:0000313|EMBL:SDJ92868.1};
KW   Nuclease {ECO:0000313|EMBL:SDJ92868.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:SDJ92868.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199155}.
FT   DOMAIN          172..259
FT                   /note="RecD helicase-like helix-hairpin-helix"
FT                   /evidence="ECO:0000259|Pfam:PF14490"
FT   REGION          1..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        81..102
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        140..157
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   746 AA;  75991 MW;  6E4539259EE0F7DF CRC64;
     MSTESAAEQP RADVASEPES PEAAESTVSA GEAPAAEASA DEAGAAGGED GAGAASGGDG
     AQAADGGEKA GQPGELSEAE AELAAQRELR ERIEKRKAEK GGPIAAGGKL SGTAADLLAA
     VRAVESGEKP VTRVVAEPPA PRRPAAPEQP RPAAPAPVAP TRVVSAPPAE AVSAVRTVLA
     RGGAPEALAE RAIAVLGEGA DQQLREDPWQ LLRVSGVRPD HADGFARALL GEACGPEDER
     RGRALTGWLL EQAAVAGHTA LDAGPLKQAL AQRGVPDPDA AVESAVAEGE VLVFQDALDE
     GTPEHADAAG DEDEEAAERP VRVLFGLERY ALAEESLADG LARVVNGLEK EAGSDLAGWA
     EAAGSVRGSA AELIRASAAH GLVLHTGGEA ARAETAALLG AARELGLRVC AATHTPDGRR
     RLAQAHGLAE VVTVAGLLSD NEGPGRDAEG ALQLDLLVVL DAPQLDVETA AMLVESLADG
     ARLVLSGDPA VLWSAGAGRV FADLLAARVC PQVTSRTPDP GPIGELVSGI TIGELNQVEA
     PGKEVVIVPA RDPGEAVHRT VQLVADSIPR ACSVPAEQTQ VITVAHGGPA GTRALNAALK
     ERLNPGPGRF GGFDPGDRVS YTPAPGRTVT GLVTGAEAAG LRLDVEGASV VVPKEQVEER
     VRHGWALTAH QALGHRWPAV VAVLPGDAAA TLTRAWVYSA FSRAERHLSV VHGVEGALAR
     AVAEIPSKPR TTRLERLLKG QVPAAV
//